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OPTIVE
Transcript
Evaluation of the effects on conjunctival tissues of Optive eyedrops over one month usage
Methods
RESULTS / OUTCOMES
ALLERGAN
PRODUCT: Optive
BULBAR
- Findings showed that although staining at the start of the investigation was similar, staining after one month use was significantly less with Optive than Hylocomod (P=0.028 – 0.002)
LIMBAL
Examples of conjunctival staining photography with Lissamine Green
Study Author: M. Guillon et al
CONCLUSIONS
GROUP 6
BACKGROUND
- Results clearly demonstrated that the regular use of Optive over a month period was significantly superior to Hylocomod in improving conjunctival status by producing a greater reduction in the staining of dry eye sufferer
- Reversal in conjunctival staining with Optive indicates that the ocular surface has returned to a normal state and is an important marker of efficient management of the condition that goes beyond symptomatic relief.
- In addition, Optive incorporates three osmoprotectants (Glycerin, L-Carnatine and Erythritol) which are reported to act directly at the cellular surface providing a more hydrated environment.
STUDY TITLE
PATIENT PROFILE
.
Art
Love
Ferchee
Cath
Published in Contact Lens & Anterior Eye, 2010
OBJECTIVE:
The population was made up of 47 subjects
(21 male and 26 females) aged 42 + 16 years
with at least mild dry eye symptoms and
conjunctival and or corneal staining;
this included contact lens wearers (26) and non-wearers (21)
STUDY DESIGN
Randomized , bilateral, single-masked, group comparison dispensing study on one month duration
VS
METHOD
Subjects were randomly allocated to use one of the two study products
(Optive = 21, Hylocomod = 26) and instructed to use the products as often as needed but at least 3x/day.
Conjunctival staining was rated on forced choiced scales and measured objectively using digital photographs and image analysis.