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West Kazakhstan State Medical University named after Marat Ospanov
Department of general medicine practice №1 with a course of communicative skills
In recent years, much attention is paid to studying of variability (dispersion) of the QT interval of the repolarization as the increased variance of the QT interval is also a factor in the development of a number of serious rhythm disturbances, including sudden death.
During the study, 56% of patients after using antiarrhythmic drugs found a change in the corrected QT interval.
Therefore, when prescribing antiarrhythmics, it is necessary to remember the possibility of increasing the risk of patients death with altered intervals of QT. In the case of prolongation of the QT interval, it is advisable to review the treatment strategy by choosing alternative pharmacotherapy, to control drug interactions that can worsen prognosis, bradycardia and electrolyte disturbances.
The study was conducted on the basis of the Ambulance hospital in Aktobe and at the Medical Center of the WKSMU named after Marat Ospanov of the Cardiology Center.
A retrospective analysis of the case histories of 74 patients with ischemic heart disease and Hypertensive disease II and III degree: Confirmed by clinical, laboratory data, typical ECG changes from November 2016 to March 2017.
Before the start of the medication, ECGs were done, in 74 patients the QT interval was 0.33-0.37, the corrected QT was 0.45-0.47.
Of these diseases, it is worth noting that they took such drugs as Bisoprolol, Diltiazem, Verapamil, which over time directly influenced the QT interval.
Zh. Zh. Sayemkozhina , M. Amanzholkyzy
The study of parameters of the corrected QT interval from ECG data in patients with IHD, as well as an assessment of the risk of adverse outcomes with prolongation of the QT interval and an increase in its dispersion to identify pro-arrhythmic effects of antiarrhythmic drugs.
Scientific Advisor – Candidate of Medical Science T.N. Zhumabayeva