Audio Transcript Auto-generated
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Hi welcome to my presentation. My name is Haley's Eagle.
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And today I'll be presenting about the paper called temporal shifts in the skin
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microbiome associated with disease layers and treatment
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and Children with a topic dermatitis or basically
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the microbiome and a topic dermatitis.
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So what is a topic dermatitis or A. D. For short?
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A. D.
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Is an inflammatory skin disease characterized by red itchy dry patches of skin.
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It is chronic and worsens during flare ups. So as of right now there is no cure for it.
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While it has been associated with the bacteria staphylococcus aureus or S. Aureus.
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For short,
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the role of the skin's normal bacterial community
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of the microbiome and the progression of A.
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D. Has not been studied as deeply.
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So scientists set out to form a more holistic view of A. D.
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In the context of the skin's microbiome as a whole.
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In order to analyze this relationship,
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skin and nasal swabs were collected to record the abundance
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of bacteria at different stages of the disease process.
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The swabs were analyzed via bacterial gene analysis and it
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was conducted on samples of Children affected with A.
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D.
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Here the graph representing the findings during a flare up the levels of S.
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Aureus rise substantially becoming the majority of the represented microbiome.
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After treatment. S aureus levels decrease becoming lower than a baseline.
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So what are some of the outcomes of this
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by determining how much and how many varieties of
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different bacteria were present before and after flare ups.
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It was found that lower bacterial diversity due to staff was linked with a. D.
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Flares.
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It is suggested that A. D. Therapies may have to diversify the skin microbiome.
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Thinking about the current treatments for both A. D.
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And how they subsequently affect both bacteria and disease activity can help
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us reduce the use of antibiotics and thus the phenomenon of antibiotic resistance
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in the larger scope of working with humans and their microbiome,
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understanding the relationship and influence of the bacteria in and on our
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bodies can help us find new strategies to improve our health.