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Chapter 1
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    Hi welcome to my presentation. My name is Haley's Eagle.

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    And today I'll be presenting about the paper called temporal shifts in the skin

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    microbiome associated with disease layers and treatment

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    and Children with a topic dermatitis or basically

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    the microbiome and a topic dermatitis.

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    So what is a topic dermatitis or A. D. For short?

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    A. D.

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    Is an inflammatory skin disease characterized by red itchy dry patches of skin.

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    It is chronic and worsens during flare ups. So as of right now there is no cure for it.

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    While it has been associated with the bacteria staphylococcus aureus or S. Aureus.

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    For short,

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    the role of the skin's normal bacterial community

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    of the microbiome and the progression of A.

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    D. Has not been studied as deeply.

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    So scientists set out to form a more holistic view of A. D.

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    In the context of the skin's microbiome as a whole.

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    In order to analyze this relationship,

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    skin and nasal swabs were collected to record the abundance

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    of bacteria at different stages of the disease process.

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    The swabs were analyzed via bacterial gene analysis and it

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    was conducted on samples of Children affected with A.

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    D.

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    Here the graph representing the findings during a flare up the levels of S.

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    Aureus rise substantially becoming the majority of the represented microbiome.

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    After treatment. S aureus levels decrease becoming lower than a baseline.

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    So what are some of the outcomes of this

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    by determining how much and how many varieties of

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    different bacteria were present before and after flare ups.

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    It was found that lower bacterial diversity due to staff was linked with a. D.

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    Flares.

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    It is suggested that A. D. Therapies may have to diversify the skin microbiome.

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    Thinking about the current treatments for both A. D.

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    And how they subsequently affect both bacteria and disease activity can help

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    us reduce the use of antibiotics and thus the phenomenon of antibiotic resistance

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    in the larger scope of working with humans and their microbiome,

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    understanding the relationship and influence of the bacteria in and on our

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    bodies can help us find new strategies to improve our health.