Audio Transcript Auto-generated
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transcription.
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The central dogma of biology
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describes the genetic flow of information
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from DNA
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to RNA.
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Two proteins,
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more specifically.
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The central dogma states
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that DNA produces DNA
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through the process of replication.
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It states that DNA produces RNA
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through transcription
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and that RNA produces proteins through translation
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in transcription.
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There is the template strand.
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This is the transcribed DNA.
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There's also the coding strand
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which is the un transcribed DNA strand.
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The transcription bubble is where the DNA is unwound
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and the complementary RNA strand is built.
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The RNA polymerase
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is the enzyme that facilitates the RNA synthesis
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in the initiation phase.
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RNA polymerase binds to the promoter sequence.
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The promoter sequence
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determines where the RNA synthesis starts.
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It determines which DNA strain will be the template
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and which one will be the coding
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and it determines the direction of synthesis
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depending on which is a template
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Synthesis always occurs in the 5-3 direction
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during elongation.
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The RNA polymerase unwinds the DNA 20 base pairs at a time
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and joins the complimentary messenger RNA.
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No proof reading of the product is necessary.
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This is because
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there is a little error.
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There are many copies
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and it has short life
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in RNA. We have to remember that day I mean is always replaced with the euro cell
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after the RNA is complete.
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The termination sequence
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signals the RNA polymerase
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to stop synthesizing the M. RNA strand.
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The completed M. RNA
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then leaves the nucleus through the pores
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After transcription and eukaryotic cells
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processing of the M. R. N. A. Still needs to occur
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AGI cap and a poly a tail are added to the ends of the M. RNA.
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In order to protect it from enzymes
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that are found in the cytoplasm.
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Then
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the introns are edited out and the exons are sliced together.
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The interns are the non coding sequences
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and the exons are the coding sequences.
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The result of spicing together the enzymes
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is a mature M. RNA strand
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spices zones which are made up of several snR and PS.
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Recognize the spice site sequence
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and ended out. The introns.
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S. N. R. And P. S. Are small nuclear RNA
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made up of proteins and RNA
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after post transcription processing in eukaryotic cells
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and transcription and new periodic
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and procure erotic cells.
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You have translation
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translation occurs in ribosomes
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after transcription.
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The ribosomes are made up of two sub units, the small and the large
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within translation
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you have. T. RNA is pairing the anti cardin's with the Kardashians.
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This results in the formation of a polyp peptide chain
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In translation.
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There are four steps
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activation
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initiation,
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elongation
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and termination.
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There are also three sites and translation.
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There's amino acid
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a site,
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there is the polyp peptide p site
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and the exit
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east side
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that makes up translation.