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Grey Literature
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Major types of grey lit:
- Registered Clinical Trials and Research
- Conference Abstracts and Proceedings
- Dissertations & Theses
- Research via Open Access
- Reports
- Experts and Researchers
Want to know more about the real effects of publication bias?
Ben Goldacre: What doctors don't know about the drugs they prescribe. Jun 2012
http://bit.ly/T92Rlq
Step 1: Pull out search terms
postmenopausal osteoporosis
drug therapy
quality of life
Let's take a look at
http://clinicaltrials.gov
More sources of grey literature:
Regulatory Data:
US Food and Drug Administration
http://www.fda.gov/Drugs/default.htm
European Medicines Agency
European Public Assessment Reports-Human (EPAR)
http://bit.ly/ro3EXu
Freedom of Information Act (FOIA)
http://1.usa.gov/2oO9ex
Research Registers:
NIH Reporter
http://projectreporter.nih.gov/reporter.cfm
HSRProj : Health Services Research Projects in Progress http://wwwcf.nlm.nih.gov/hsr_project/home_proj.cfm
United Kingdom Clinical Research Network (UKCRN)
http://public.ukcrn.org.uk/search/ (2012- )
National Research Register (NRR) Archive (2000-2007)
www.nihr.ac.uk/Pages/NRRArchiveSearch.aspx
A fixed copy with no amendments or corrections to be made.
Canada: Canadian Research Index (by ProQuest subscription/Microlog) - catalogue of Canadian federal, provincial, territorial, regional, and local government publications.
General Resources:
- New York Academy of MedicineGrey Lit Report
Home, dedicated search http://www.greylit.org/home
Catalog Search http://www.nyam.org/library/
- OAIster (pronounced "oyster")
OAI = Open Archives Initiative
Harvests metadata from over 1,100 participating open archives
Free search: http://oaister.worldcat.org
Description: http://www.oclc.org/oaister/
http://gateway.nlm.nih.gov/gw/Cmd
http://www.biomedcentral.com/bmcproc
Grey Literature in the Health Sciences
Photo by The Colour Between http://www.flickr.com/photos/38029248@N00/1914266700/
Clinical Trials Registries
- ClinicalTrials.gov
- http://clinicaltrials.gov
- WHO International Clinical Trials Registry Platform (ICTRP)
- http://apps.who.int/trialsearch
- includes European Clinical Trials Register, updated weekly
- https://www.clinicaltrialsregister.eu
- International Federation of Pharmaceutical Manufacturers & Associations (IFPMA) Clinical Trials Portal http://bit.ly/g6FHjP
- NIPH Clinical Trials Search (National Institute of Public Health - Japan) http://rctportal.niph.go.jp/en/index
- Eli Lilly’s ClinicalCollections (Beta) http://www.clinicalcollections.org/trials/
Image by Tom Varco
Activity:
Dr. Grey is conducting a systematic review of drug therapy for osteoporosis in postmenopausal women, but is not sure what resources to use to retrieve results from clinical trials, unpublished research, and other grey literature. Dr. Grey is particularly interested in looking at quality of life outcomes.
Help Dr. Grey find resources from the grey literature by searching one of the clinical trials registries.
Activity: Choose one of the following registries
and complete the evaluation sheet.
1. WHO ICTRP http://apps.who.int/trialsearch/
2. Eli Lilly’s Clinical Collections (Beta) http://www.clinicalcollections.org/trials/
3. NIPH Clinical Trials (Japan) http://rctportal.niph.go.jp/en/index
4. IFPMA Clinical Trials Portal
http://bit.ly/g6FHjP
To find the top authors
and top journals in a field:
- GoPubMed
http://gopubmed.org/web/gopubmed/
Acknowledgments:
This presentation was adapted from a presentation at the Systematic Review Workshop: The Nuts and Bolts for Librarians, Health Sciences Library System, University of Pittsburg, Nov 12-14, 2012
Grey Literature presentation by Andrea Ketchum, MLIS and Barbara Folb, MM, MLS, MPH
What is grey literature?
1997- The Luxembourg Convention on Grey Literature; expanded New York 2004
“that which is produced on all levels of government, academics, business and industry in print and electronic formats, but which is not controlled by commercial publishers i.e. where publishing is not the main activity of the producing body”
GreyNet (www.greynet.org/greynethome/listserv.html)
Synonyms
Gray literature
Fugitive literature (http://lostdocs.freegovinfo.info)
Why search grey lit?
- Reduce publication bias
- Incorporating unpublished trial data can change statistical results
- Current systematic review standards call for grey lit inclusion