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Do you know that Agendia accessed untreated tumor samples with 10-year patient follow up and known outcomes? The signature development process began by identifying two patient groups; those who developed distant metastases within 5 years and those who were cancer-free at 5 years. The entire human genome identified. The resulting difference in gene expression pattern was captured in an 18-gene signature – ColoPrint.
Symphony Colon Cancer Profile
Poster
ColoPrint
launching by
Patient Brochure
Sample Reports
Colon Cancer
Gene Expression Signature
Low Risk
Colon Cancer
Gene Expression Signature
High Risk
To date, CP has been clinically validated in over 1,000 patients in four independent studies in Europe and the U.S. and is the subject of the PARSC prospective study, ongoing since 2008. These studies have shown that gene expression profiling is superior to current criteria for determining the risk of colon cancer recurrence.1 In several independent studies, CP was compared to all relevant clinical factors (age, gender, localization of tumor, grade, less than 12 lymph nodes assessed, and T-stage) and to a combination of the factors that define patients as high risk according to ASCO recommendation or NCCN guidelines. In all studies, ColoPrint was the most significant and strongest factor for predicting recurrence.
ColoPrint provides 100% actionable result – Low or High Risk
Specimen Sampling Instructions
(cc) image by nuonsolarteam on Flickr
7.
Completing the test requisition form
You will be notified once we receive the Agendia test result.
4.
Instructions for using the punch biopsy tool.
5.
Sampling tips and choosing the sampling site
Pre-surgery preparations
1.
3.
Obtaining a sample from a surgical specimen
The fresh, unfixed tumor specimen must be delivered to pathology immediately following surgical removal.
6.
Packaging the sample for shipment
Ship at room temperature; do not freeze the sample.
2.
Specimen collection and transportation kit
The sample must be obtained within 1 hour of surgical removal.
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