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Brief history of cell biology
Transcript of Brief history of cell biology
1665 - Robert Hooke
English philosopher, architect & polymath
In September 1665 (aged 30), Hooke published Micrographia
Coined the term “cells” to describe “tiny boxes” (honeycomb) in cork
Thought only existed in plants & fungi
1673 - Anton van Leeuwenhock
Dutch tradesman & scientist
Pioneer in microscopy
Invented 25 different types of hand-made microscopes
Observed unicellular microorganisms (“animacules”) in pond water
Observed blood cells in vertebrates
1674 – protozoans (protista)
1676 – bacteria
1677 – vacuole
1677 – spermatozoan
1682 – striated muscle fibres
c.560 letters to the Royal Society
1838 - Matthias Schleiden
Concluded all plant parts are made of cells
1839 - Theodor Schwann
Stated that all animal tissues are made of cells
1858 - Rudolf Virchow
Didn’t accept popular theory of spontaneous generation
Concluded cells arise from pre-existing cells
19th Century - Cell theory postulate
All organisms consist of one or more cells (Schleiden & Schwann)
The cell is the basic structural unit of all organisms (Schleiden & Schwann)
All cells arise from preexisting cells – “omnis cellula e cellula” (Virchow)
Cell theory postulate not only holds the cell to be the smallest living entity (the fundamental unit of life), but to be the basis for reproduction!
1950 - Watson & Crick
The cell contains the hereditary information (DNA) which is passed from cell to cell during cell division
Modern cell biology at cross-roads of