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Copy of Asthma
Transcript of Copy of Asthma
Trade Names: Proventil, Ventolin
Chemical Name: C13H21NO3
Function Classification: sympathomimetic, bronchodilator, beta2-adrenergic To prevent and treat wheezing, shortness of breath, coughing, and chest tightness caused by asthma Presented By: Sam Rita Mary Jacquelyn Chantel References Edmunds, Marilyn W (2010). Introduction To Clinical Pharmacology. 6th Edition. St. Louis, MO: Mosby/Elseveiver. Skidmore-Roth, Linda. (2011). Mosby's Drug Guide for Nurses, Ninth Edition. St. Louis: Elseveiver Mosby Central Nervous System nervousness restlessness tremor headache insomnia paradoxical bronchospasm chest pain palpitations angina arrhythmias hypertension nausea vomiting hyperglycemia hypokalemia Respiratory System Cardiovascular System Gastrointestinal System Endocrine System Fluid & Electrolye hyperactivity in children Theophylline Result: toxicity Oxytocics Result: severe hypertension Diuretics (potassium losing) Result: EOG changes/ hypokalcomia MOIs possibility of hypertensive crisis Antidepressant (tricyclic) Result: possible hypertension Beta Blockers Result: therapeutic effect blocked Adrenergics Result: the action of albuterol Drug Classification Drug/Herb Interaction Drug/Food Interaction chocolate caffeine products Result: stimulation black tea green tea cola nut guarana yerba mat'e Instruct patient to take med as directed Instruct patient to prime unit Notify health care profressional of all RX and OTC meds Albuterol may cause unusual or bad taste Pharmacokinetics
(How drugs circulate) Absorption: Tablets are rapidly absorbed. Food absorption rate. 20% is absorbed though inhalation 3D view 2D view Breathing Process What is asthma? Do not exceed recommended dose
PO Administration: with meals Assess: lung sounds, pulse, and BP Distribution Gradual absorption= systemic levels are Metabolism extensively in the liver Pharmacodynamics (how drugs act) stimulates the beta2-adrenergic receptors airway constriction Excretion Half-life: 4-6 hours Oral: 60% metabolized and excreted in the urine Inhalation: 80-100% renally excreted
4-20% excreted through feces Lippincott, Williams, and Wilkins (2013). Nursing Pharmacology made Incredibly Easy. 3rd Edition. Ambler, PA: Wolters Kluwer.