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Exploring DNA

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by

Andreea Temelie

on 28 March 2015

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Transcript of Exploring DNA

Exploring DNA
The Basics
General Ideas
DNA stands for Deoxyribonucleic Acid

Found in the nucleus of all cells

Purpose:
Instructions for all living things (by making proteins)
DNa ---> RNA---> protein
DNA -- transcription---> RNA
RNA--- translation---> Protein
Carry on heritable information (genes)
Components
Shape: double helix
Compared to ladder with rungs
backbone: sugar & phosphate

4 Bases:
Adenine, Thymine, Guanine, Cytosine
2 Types: Pyramidines & Purines
Complementary Pairs held by Hydrogen Bonds

Nucleotide= 1 base, 1 phosphorous group, & 1 sugar group
DNA Replication
Lets Make Our Own DNA!
2 pieces of licorice:
2 sugar phosphate backbones
12 toothpicks
Marshmallows: The 4 Bases
9 pink marshmallows
9 yellow marshmallows
9 green marshmallows
9 orange marshmallows
The Marshmallows
Adenine (A) = Green
Thymine (T) = Pink
Cytosine (C) = Yellow
Guanine (G) = Orange

Our sequence: T A C G T A T G A A A C
Putting it Together
1st Backbone: Put a marshmallow on the toothpick and then
stick the toothpick into the licorice. Then slide the second matching marshmallow onto the toothpick
Remember A with T and C with G!
2nd Backbone: Attach the second piece of licorice to the toothpicks so that it looks like a ladder
-What is DNA?
-Where is it found?
-What is it made up of?
-Why is it important?
Then carefully twist to form a double helix!
1.Helicase : unwinds DNA
2.DNA polymerase III works down leading strand(old strand) up lagging strand(new strand)
a.Pair free nucleotides with complementary bases b.Complementary bases= A&T and G&C
3.DNA is successfully copied
a.original & copy each contains one strand of original DNA
1.


2.



3.



4.
Animation of DNA Replication
Image
of DNA
T
A

C
G
T

A

T

G
A A A

C
me
Full transcript