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Early Results from the Newfoundland and Labrador Bariatric Surgery Cohort Study

PriFor November 26, 2012
by

Kendra Lester

on 25 November 2012

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Transcript of Early Results from the Newfoundland and Labrador Bariatric Surgery Cohort Study

Obesity in Newfoundland & Labrador Early Results from the Newfoundland and Labrador Bariatric Surgery Cohort Study (NL BaSCo Study) An Effective Treatment Who is getting LSG in NL? Table 1. Baseline Demographics (n=74) Table 2. Comorbidity Profile & Quality of Life (n=72) Results: Weight Loss Measures Table 3. Changes in Weight Loss Measures Figure 4. Changes in Patient
Allocation to BMI Category Post-Surgery Figure 3. Percent Excess Weight Loss and Percent Change in Total Body Weight Post-Surgery Figure 2. Quality of Life Measured by the EQ-5D
(n=72) Figure 1. EQ-5D Visual Analogue Scale Results: Quality of Life Outcomes Figure 5. Changes in EQ-5D VAS Scores 6 Months Post-Surgery (n=25) Mean = 79.3 (13.2) Mean = 60.4 (20.1) Baseline 6 Months Figure 6. EQ-5D Results 6 Months Post-Surgery (n=31) Thank You! Results: Improvements in Comorbid Conditions Kendra Lester (MSc Can.) Obesity is a health condition where the natural energy reserve stored in the fatty tissue is increased to a point where it is thought to be a risk factor for certain health conditions. These conditions include: Hypertension Cardiovascular Disease/MI Type 2 Diabetes Mellitus Sleep Apnea Cancer GERD Premature Mortality In NL 27.7% of the population, or 1 in 3 adults, is obese. 8% of NL's adult population has a BMI ≥ 35. ~75% of this population report having > 3 chronic conditions. The highest prevalence in Canada. That's ~29,800 people. Disclosure: Questions? Type 2 Diabetes Mellitus Defining Glycemic Control Prediabetes: FPG 6.1 - 6.9 mmol/L
A1c 5.7 - 6.4% T2DM: FPG ≥ 7.0 mmol/l
A1c ≥ 6.5% Table 4. Glycemic Control at Baseline (n=66) Within 6 Months Post-Surgery Of the 11 prediabetic patients who have completed follow-up:
8 (72.7%) have A1c < 5.7%
11 (100%) have FPG < 6.1 mmol/L

Mean A1c has decreased by 0.6%
Mean FPG has decreased by 1.0 mmol/L Of the T2DM patients who have completed follow-up:
12 of 19 (63.2%) have A1c < 6.5%
14 of 17 (82.4%) have FPG < 7.0 mmol/L

Mean A1c has decreased by 1.5%
Mean FPG has decreased by 2.0 mmol/L Dyslipidemia Table 5. Changes in Lipid Profile The NL BaSCo Study declares no conflicts of interest.

The study is funded by the Newfoundland and Labrador Centre for Applied Health Research (NLCAHR) through a project grant and receives in kind funding from Eastern Health. Bariatric (weight loss) surgery is the only known effective treatment for obesity. MCP (DHCS) agreed to fund 70-100 laparoscopic sleeve gastrectomy (LSG) procedures a year which commenced at Eastern Health in May 2011. Eligibility Criteria BMI ≥ 35 with risk factors BMI ≥ 40 OR BMI < 18.5: Underweight
BMI 18.5 - 24.9: Normal
BMI 25.0 - 29.9: Overweight
BMI ≥ 30: Obese NL Bariatric Care Translational
Research Team Eastern Health established a multidisciplinary team to help care for patients Research began under the direction of the Principal Investigator (PI), Dr. Laurie Twells, and Co-PI, Dr. Debbie Gregory. 1-2 hour surgical procedure Removes ~80% of the stomach leaving behind a "sleeve" (60-100 mL) 3 surgeons
Nurse Practitioner
Dietician Patients are assessed at baseline and 1, 3, 6, 12, 18, and 24 months post-surgery
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