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Parkinsons Disease

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on 20 November 2015

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Transcript of Parkinsons Disease

Alicia Cabrera Olvera
MW 8am

Parkinson's Disease
Anatomy of Nervous System
Physiology of Nervous System
Anatomy of Parkinson's Disease
Physiology of Parkinson's Disease
Diagnosis of Disease
Who is at Risk ???
Detection of important Signs& Symptoms
Signs & symptoms !
The brain & spinal cord:

Usually the professionals give a "
Clinical Diagnosis
," due to they cant really confirm it

Neurologic Exam: Observes the patients
MRI & CAT Scans: There results appear to be normal
EEG'S: records brain electrical activity. But not effective when spotting for parkinsons.
involuntarily trembling
muscles: rigid & stiff
unable to make rapid movement
walking with a gait: meaning the body is bent
difficult maintaining balance
Speech problems
Writing problems
Genetic Factor
Environmental Factors
Genetic Factor
polymorphism is a gene that appears to increase the risk of PD

15 -25% of people that have PD relative w/ it too

People w/ affected first degree relative (means parents or siblings) have a 4 - 9% of higher chance of PD

Environmental Factor
Being espoused to toxins
Prolonged occupational exposure to chemicals
1980s in people that injected themselves w/ a synthetic in form of heroin that was contaminated with MPTP caused PD
This form is rare
Rarely Adults
Middle aged & the Elderly
if you have a relative that had it your at higher risk
Men most likely to get it than women
Facial expression changes; less blinking
Unable to swing arm when walking
Stooped posture
Softness of voice
Painful shoulders "Frozen"
Parkinson's Disease
What's Dopamine?
Brain & Spinal Cord
Central N.S. & Peripheral N.S.
the brain lobes are:
As well as within the brain are :
mid brain
medulla oblongata
spinal cord
Substantia Nigra
Anatomy of Substantia Nigra
A neurotransmitter that helps in transmission of signals in the brain & other vital signs & daily activities
Located at the base of the mid brain
Controls movement & coordination
Center of communication
- Communication occurs through Neurotransmitters
What are Neurotransmitters & how they work ?
Certain chemicals that help send signals from the brain to the rest of the body.
Some Neurotransmitters are:
Part of the basal ganglia
What do cells produce?
The cells in the Nigra produce Dopamine
What's Parkinson's Disease??
- Chronic progressive disorder of degeneration of dopamine production
Long term effect
lost of dopamine
several effects
Damaged brain part
How the substantia nigra looks
How the neurons don't produce enough dopamine
Review of parkinsons signs disease
Progreesive long term effect
Unknown cause : gentics & enviormental factors
Main S&S is tremors, weak movement etc.
Treatments: medications to supply more dopamine & to reduce/ improve tremor or surgery as last resort
Review video of Parkinson's Disease
Treatments (:
Lack of dopamine
No Strong Signal
Review of PD
No cure but medications can help you
control your symptoms.
improve waliking
Less tremors: dopamine supply
Names of medications:
Carbidopa- levodopa
Dopamine agonists
Other suggesten for further PD
is surgery
Treatment explainations:
Carbidopa Levodopa:
- Chemical that passes throught your brain
& as it passes it converts into dopamine
More dopamine !
Dopamine Agonists:
- Mimics the effects of dopamine( meaning it dose the same job as dopamine)
- This medications helps control the tremors one has ......MIGHT reduce tremors
PD Disease
Not very effective
Systems Affected

Muscular System :
Skeletal System:
Bones will become weak
Full transcript