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DNA Replication Project

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Jessica P

on 5 February 2013

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Transcript of DNA Replication Project

By: Jessica Perez-Manrique DNA Replication Inside an Animal Cell Base Pairs and the Sturcture of DNA Nucleotide(s)- in a nucleic-acid chain, a subunit that consists of a sugar, a phosphate and a nitrogenous base
Nitrogen bases-an organic base that contains nitrogen, such as a purine or pyrimidein; a subunit of a nucleotide in DNA and RNA
phosphates-composed of phophorus and oxygen and plays a major role in the biological processes of many organisms and links 5 carbon sugars
deoxyribose-a sugar The beginning and the Leading strand DNA Replication-the process of making a copy of DNA
Helicase-an emzyme that separates DNA strands
DNA Polymerase III-adds deoxyribonucleotides to the 3' end of the RNA primer.
DNA Polymerase I--an enzyme that catalyzes the formation of the DNA molecule
single stranded binding proteins-proteins responsible for holding the replication fork and preventing the DNA strands from binding back together.
replicaiton fork-structure that forms within the nucleus during DNA replication
leading strand-DNA strand that is synthesised continuously during replication
lagging strand-DNA strand that is replicated discontinuously from the 5' to the 3' direction. This is what the inside of a cell looks like. We could take a closer look at all of these organelles but right now we are going to go deeper inside the cell into the world of the cell nucleus. The animal cell Key words I. DNA- Deoxyribonucleic acid, it is a self-replacing material present in nearly all living organims
genes-a short segment of DNA that contains the instructions for a single trait.
genetic code- the rule that describes how a sequece of nucleotides specifies the animo acid sequence of a protein.
chromosomes-rod shaped sturctures that are made up of DNA and proteins
Nucleus---->Chromosomes---->DNA---->Genes---->Genetic code In side of the world of the cell nucleus we take a trip to the city of chromosomes then we take a ride on DNA street and for this trip we stop before we get to gene avenue. Fasten your seat belts!! Key words The sturucture of DNA Base Pairs Under the base pairing rules cytosine(C) pairs with guanine(G) and adenine(A) pairs with thymine(T) in DNA. As you can see here DNA is structured in a double helix which is kind of like a twisting latter composed of nucleotides. Key words First helicase unwinds a segment of the DNA and breaks the hydrogen bonds between the two strands of DNA. DNA polymerase adds new nucleotides to a free 3' end of a growing chain. So synthesis of the leading strand continues in the 5' to 3' direction. Lagging strand Leading Strand RNA primase attaches to the DNA and synthesizes a short RNA primer. DNA polymerase III then comes and adds deoxyribonucleotides to the 3' end of the RNA primer DNA polymerase III is then replaced by DNA polymerase I which removes the RNA and replaces it with DNA * okazaki fragments are relatively short fragments of DNA synthesized on the lagging strand Lastly the enzyme DNA ligase forms a phophodiester bond between 3' OH of the growing strand and the 5' phosphate that is infront of it. Summary and Conclusion
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