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SWEDEN

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by

yosra kamal

on 21 March 2015

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Transcript of SWEDEN

ABSOLUTE UTERINE FACTOR INFERTILITY
Costy
Multiple Trials
Miscarriage
Costy
Miscarriage
Multiple Trials
NO GESTATION
ABSENT UTERUS
Prepare
like-
vessels
D O N O R
RECIPIENT
BABY
HLA
Immuno-
suppression
M A L I G N A N C Y
Myoma
Bleeding
A d h e s i o n
Malformation
Radiation
Flushing

Uterus:without atypia
no H/O of cervical dysplasia
Age is of minor concern
extended arterial supply
long veins and ligaments
UTERINE TRANSPLANT
T H E F I R S T B A B Y B O R N
THE 16TH ANNUAL CONFERENCE OF THE DEPARTEMENT OF GYNAECOLOGY & OBSTETRICS
MARCH 2015
Tahany
Emma
They had their hysterectomies done 5 years ago
Sam
Hysterectomy
Back- table vessel
preparation
(mother/
mother sister)
Transfer Embryo
Uterine Transplant has given hope to many ladies who thought they will never be able to get pregnant and experience a full motherhood..
"
"
BUT!
Anastomosis
& Fixation
NON
FUNCTIONING
M A T C H I N G
IVF success
Ovarian Reserve
necrotic uterus
poor (fixation/ anastomosis)
2000
SAUDI
ARABIA
T U R K E Y
2011
Donor was a brain dead heart beating woman
Good (fixation/ Anastomosis)
The research team in Turkey reported several attempts to reintroduce embryos and two very early pregnancies that ended in miscarriage.
2013
S W E D E N
The patient was admitted with pre-eclampsia at 31 full weeks and 5 days, and 16 h later a caesarean section was done because of abnormal cardiotocography. A male baby with a normal birthweight for gestational age (1775 g) and with APGAR scores 9, 9, 10 was born.
2014
The Sahlgrenska University Hospital
THE UTERUS TRANSPLANTATION RESEARCH PROJECT
Seven Swedish women have had embryos reintroduced after receiving wombs from living donor.
One case survived with 3 mild episodes of rejection
ADOPTION
SURROGACY
1
2
3
4
5
6
8
I N V I T R O
F E R T I L I Z A T I O N
UTERINE TRANSPLANTATION
Ethical issues?
Religion? difference between UT & Surrogacy
Congenital Deformity? Long-term Side effects
Maybe Yes Maybe No
Risk of
Another Operation
Limited Benefit
R E M O V E
U T E R U S
9
Triple Relationship
Technical Point of View
Wait...
12 months of
normal menstruation
no rejection
7
Full transcript