Send the link below via email or IMCopy
Present to your audienceStart remote presentation
- Invited audience members will follow you as you navigate and present
- People invited to a presentation do not need a Prezi account
- This link expires 10 minutes after you close the presentation
- A maximum of 30 users can follow your presentation
- Learn more about this feature in our knowledge base article
Do you really want to delete this prezi?
Neither you, nor the coeditors you shared it with will be able to recover it again.
Make your likes visible on Facebook?
Connect your Facebook account to Prezi and let your likes appear on your timeline.
You can change this under Settings & Account at any time.
Neurotransmitters and neurotransmission
Transcript of Neurotransmitters and neurotransmission
Body functions are largely controlled and integrated by the central nervous system
Neurotransmission: The process by which a neuron releases signaling molecules which bind and activate receptors of another cell.
Neurotransmitter: Endogenous chemicals
released by neuron to signal
Discovery of chemical neurotransmission
Otto Loewi's experiment provided
the first evidence for the existence of chemical neurotransmission
of the synapse
Synapse: The site of chemical transmission
Life cycle of a neurotransmitter
After an action potential fires...
Classes of neurotransmitters
Glutamate, GABA, glycine
Neuroscience Core Lecture
Modifications of synaptic transmission by drugs and disease
Drugs can modulate neurotransmission at many levels
GABA: gamma-aminobutyric acid: Inhibitory
Glycine: Modulates excitatory and inhibitory
Reward and motor
Motor control and sensations
Nitric oxide and carbon monoxide
Reduce NT release
Increase NT release
endogenous opioids, substance P
DA, NE, 5-HT
Targets SNAREs on excitatory
Trauma causes cell death
Release of excess glutamate
Results in toxic calcium influx
Propagates death in surrounding