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Science Stibs

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Kapilan Ravindra

on 11 February 2011

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Transcript of Science Stibs

http://www.cnn.com/video/#/video/bestoftv/2011/02/10/exp.sanjay.young.stroke.cnn Chapter 4.1.4 Explain the consequences
of a base substitution mutation in relation to the process of transcription and translation, using example of sickle cell anemia Mutations are random rare changes in genetic material. A base substitution mutation involves a change of the sequence of bases in DNA. The changing of a single base in means a completely different amino acid being placed in an polypeptide chain http://highered.mcgraw-hill.com/sites/0072556781/student_view0/chapter11/animation_quiz_3.html The changing of just one amino acid could have major implications on the organism's physical characteristics. As seen here :) Hi valaria You looking good today mami In humans, once example of a mutation is sickle cell disease. In Sickle Cell disease, there is a mutation in the gene that creates haemoglobin. Haemoglobin help give red blood cells their shape,and Sickle Cell disease give a different shape to the haemoglobin molecule which therefore gives the red blod cells a different shape. In sickle cell disease, during translation the codon GAG becomes GTG, changing the amino acid Glutamic acid to valine. DON'T FORGET CHARLES DARWINS BIRTHDAY IS TOMMORROW!!!
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