Loading presentation...

Present Remotely

Send the link below via email or IM

Copy

Present to your audience

Start remote presentation

  • Invited audience members will follow you as you navigate and present
  • People invited to a presentation do not need a Prezi account
  • This link expires 10 minutes after you close the presentation
  • A maximum of 30 users can follow your presentation
  • Learn more about this feature in our knowledge base article

Do you really want to delete this prezi?

Neither you, nor the coeditors you shared it with will be able to recover it again.

DeleteCancel

ERS/ATS standarisatie

No description
by

Melissa VanHaren

on 25 April 2014

Comments (0)

Please log in to add your comment.

Report abuse

Transcript of ERS/ATS standarisatie

standarization steps
subject manoeuvre
have subject assume the correct posture
attach nose clip, place mouthpiece and close lips around it
inhale completely and rapidly with a pause of <1 sec at TLC
exhale maximally until no more air can be expelled, while remaining in the upright posture
repeat instructions as necessary
repeat for a minimum of three manoeuvres and a maximum of eight
check repeatability and perform more manoeurvres
within manoeuvre criteria
free from artefacts
cough during first second of exhalation
glottis closure that influences the measurement
early termination or cut-off
effort is not maximal throughout
leak
obstructed mouthpiece (tongue)
they have good starts
extrapolated volume < 5% of FVC or 0.15 L, whichever is greater
equipment validation
subject manoeuvres
measurement procedures
acceptability
repeatability
interpretation
They show satisfactory exhalation
duration of >= 6 s or
a plateau in the volume-time curve or
subject cannot continue to exhale or
subject should not continue to exhale

Between manoeuvre criteria
The two largest values of FVC must be within 0.150 L of each other
The two largest values of FEV1 must be within 0.150 L of each other
PEF
The PEF values and their order must be recorded so that manoeuvre-induced bronch0spasm can be detected.
between manoeuvre evalutation
two out of the first three acceptable blows should be with in 0.67 L/s if not:
two additional blows can be performed.
95% of healthy untrained subjects within 0.67 L/s
90% of healthy untrained subjects within 0.50 L/s
if not met more then 5 attempts will not be helpfull
FEF 25-75 %
The mean forced expiratory flow between 25% and 75% of FVC (mid-expiratory flow)
taken from manoeuvre with largest sum of FEV1 and FVC
accuracy:
5% of reading or 0.200 L/s whichever is greater
highly dependent on the validity of the FVC measurement and level of expiratory effort.
BTPS correction / pred. values
body temperature and pressure saturated
ambient temperature ( 10% correction factor possible)
air pressure
humidity saturation
predicate values depend on:
length
age
male / female
race (caucasian, black or asian )
why do we test?
Screening
Measurement done at screening only
exclude pathology of asthma or COPD
follow study specifics list or consult physician
Measurement done at screening and in the clinic
extra check on possibility that subject can perform a repeatable measurement within 10 minutes.
Clinic Phase and follow up
Effects of study medication present?
decrease of FVC and FEV1
increase of FVC and FEV1
patient studies
Interpertation
check tests on ERS compliance
check tests on subject entry in study.
New in equipment
Name reports
FLOW/VOLUME
FLOW/VOLUME MMEF
Reference module
Hankinson, Standard
Standard comments available in software
Hulp gevraagd
ERS / ATS standardization
Spirometry
Full transcript