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Paige McKinney

on 20 September 2013

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Transcript of Causes

Amyotrophic Lateral Sclerosis (ALS)
Tight, stiff muscles
Muscle weakness
slurred speech
Usually starts in hand, arm, or leg then spreads
May be so subtle that symptoms are overlooked
Causes/ Risk Factors
One of the most common neuromuscular diseases and people of all races and ethnic backgrounds are effected
5-10% of ALS cases are inherited
causes weakness and a wide range of diabilities
Usually does not impair a person's mind or intelligence
Eventually, all voluntary muscles are effected
There is no one test or procedure to ultimately establish the diagnosis of ALS.
It is through a clinical examination and series of diagnostic tests that a diagnosis can be established.
Examples include: X-Rays, spinal taps, muscle/nerve biopsy's, or neurological examination.
In 1995, the FDA approved the first drug treatment called Riluzole.
Riluzole helps by reducing damage to motor neurons. It prolongs life by 2-3 months but does not relieve symptoms.
Health care professionals can also design an individual therapy plan for the patient.
Basically the treatment is not guarenteed to work, it just stalls the effects of ALS.
Muscle weakness will spread throughout the body no matter where the disease originates.
Patients will begin to experience problems moving, walking, swallowing, and eventually speaking.
As muscles of the respiratory system begin to weaken, the patient has more and more trouble breathing.
Most people with ALS die from lung failure (usually about 3-5) years after being diagnosed.
10% of ALS patients live for 10+ years after the onset of symptoms.
Named after Hall of Fame baseball player, Lou Gehrig
Played for the New York Yankees
Diagnosed with ALS in the 1930s
Famous for his farewell speech referring to ALS
Lou Gehrig
ALS is a fatal disease that attacks neurons responsible for voluntary muscles.

ALS is classified as a "motor neuron disease."

In ALS, both the upper and lower motor neurons disentegrate and eventually die.
Full transcript