Normal structure and function of melanocytes (2)(3)

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by Bailey Taylor0 views·Updated May 13, 2021
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  1. Yeah, melanoma develops from mutations in melanocytes most commonly caused
  2. by UV light from the sun.
  3. Solarium melanomas begin their journey confined to the epidermis in
  4. what is termed of radial growth phase.
  5. They can be simply surgically excised during this time.
  6. Hence the importance of regular skin checks.
  7. A secondary mutation prompts the melanoma to progress deeper and
  8. it enters a vertical growth phase involving uncontrolled proliferation of
  9. melon specific cells allowing entry into the lymph or blood
  10. for extensive access to other body sites.
  11. This progression is often due to a mutation in the
  12. B raf oncogene, as this is involved in 66% of
  13. malignant melanomas measures such as Breslow thickness and clark level,
  14. as well as my topic rate, can be examined to
  15. determine the extent of exact invasiveness of a melanoma.