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by Sidra Najjar0 views·Updated Apr 3, 2022
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  1. so looking at the circumstances the world
  2. is going through and with this coronavirus pandemic
  3. to understand more about our bodies response,
  4. do this virus and to know why the fatality rate is higher
  5. with some people other than some people.
  6. So when the virus enters the body,
  7. our immune system needs to function in a
  8. way to enable the elimination of the pathogen.
  9. There are many factors that can affect this process,
  10. like ageing cardiovascular diseases, cancer it easy.
  11. So once a person is infected with covid 19,
  12. the body killer says don't function properly.
  13. It is noticed they have reduced a number and function.
  14. So when NK cells are active, it means the immune system is functioned.
  15. Probably, however,
  16. our research team found that NK cells of the average
  17. coronavirus patients where dysfunctional for patients who were severely ill
  18. So NK says, doesn't function properly
  19. even one month after they first infected.
  20. So the same concept of white Children are
  21. a sympathetic that they have larger number of
  22. NK cells.
  23. So what are NK cells? Natural killer cells are large Granules lymphocytes,
  24. which is a type of the site of toxic
  25. claim for side critical to the innate immune system.
  26. It is responsible of controlling several types of tumours and microbe Uriel
  27. infections by limiting their spread and subsequent tissue damage.
  28. So NK cells provide responses to virus
  29. infected cells and other inter cellular pathogens
  30. acting at around three days after the infection and respond to tumour formation.
  31. Typically, immune cells detect the major history
  32. history comparability complex presented an infected cell surfaces,
  33. triggering Cytoxan released,
  34. causing the death of the infected cells by licences or apoptosis.
  35. NK says are unique, however,
  36. as they always have the ability to recognise and
  37. kill stressed cells in the absence of antibodies and
  38. MHC, allowing for a much faster immune reaction.
  39. Moreover, usually only 5 to 10% in this group important rule is destroyed.
  40. Abnormal cells in the body caused by viral infections
  41. or says that have changed into cancer cells.
  42. It will be the first group of cells to search for abnormal cells
  43. without going through the process of stimulation.
  44. So overall are the natural, killer says necessarily,
  45. the number of NK cells and its function have been noticed to be reduced
  46. during virus infection, which causes the infection.
  47. Severity, functionally exhausted in cases, are the first responder of our system
  48. and when it's weak, it allows the virus to replicate and live in our bodies longer.
  49. So while on petrol, in cases constantly contact other cells.
  50. Whether or not the NK cells
  51. kill the cells depend on a balance on
  52. signals from activating receptors and inhibitory
  53. receptors on the NK cell surface.
  54. Activating receptors.
  55. Recognise Mueller clothes that are expressed on the surface of cancer
  56. cells and infected cells and switch on the NK cell.
  57. Inhibitory receptors act as a cheque on the NK cell,
  58. killing most normal healthy cells.
  59. Express
  60. M H C I receptors,
  61. which marked these cells as self inhibitory receptor on the surface of the NK cell,
  62. recognised magnet
  63. and this switch off
  64. of the NK cell, preventing it from killing.
  65. So, Casper says, and infected cells often lose their M h c I,
  66. leaving them vulnerable to NK kill selling.
  67. Yeah, sell killing.
  68. So once the decision is made to kill the NK cell release site,
  69. a toxic Granules containing per foreign and grant
  70. seems which leads to licences of the target cells
  71. To continue with hypothesis of the innate and
  72. adaptive immune response to covid 19 infection,
  73. NK cells have direct killing effect on Corona virus infected cells
  74. as well as participate and antibody dependent cellular Cytoxan Odyssey
  75. Through inhibiting and activating receptors,
  76. NK cells recognised infected cells.
  77. Once activated,
  78. the degranulation of NK says,
  79. induces the releasing of performing and grant
  80. see which directly lies infected cells,
  81. NK says, expressed C D 16 A,
  82. which participates an antibody dependent cellular statistics.
  83. Odyssey,
  84. Meanwhile, Enrique says, also interact with Democratic,
  85. says an antigen presenting process and affect adaptive immune response.
  86. So also monitor sites can secret I l six that acts
  87. as inflammatory Cytoxan,
  88. resulting in the activation of other immune cells.
  89. Don't go to conclude.
  90. In order to boost your immune system,
  91. you have to always have enough sleep and drink the right amount of motor of water.
  92. Always remember to include vitamin C in your diet and garlic specifically,
  93. and get the right amount of sunlight to increase levels of vitamin D.
  94. And don't ever forget to wear your mask properly.