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Morphine
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kristen battista
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Updated Dec 14, 2020
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00:02 - 00:03
Oh, sorry.
00:04 - 00:05
Don't Let's see you there.
00:06 - 00:11
Uh, my doctor gave me this new medicine, and I'm
00:11 - 00:13
not really sure what does.
00:13 - 00:17
I had this knee surgery the other day, and it's
00:17 - 00:20
been really, really sleepy and like, my stomach really hurts
00:20 - 00:23
all the time on like, I'm having a lot of
00:23 - 00:25
pain. Think it's called morphine?
00:27 - 00:27
I don't know.
00:28 - 00:29
So I did a little bit of research on it
00:29 - 00:31
and just what I found out.
00:35 - 00:36
So this is what morphine is.
00:37 - 00:39
It's, Ah, molecule like this.
00:39 - 00:46
And it has groups like oxygen at Benzene Ring.
00:47 - 00:48
And it's a big molecule.
00:49 - 00:54
Has, um, 17 carbons with the formula C 17, age
00:55 - 00:59
19, and 03 it's a natural substance.
00:59 - 01:05
It's extracted from the plant pap ill, ill Ephraim and
01:06 - 01:10
it's a natural plant alkaloid, and it creates an aesthetic
01:11 - 01:12
effects on the body.
01:13 - 01:16
And it was originally isolated in 18 06 by Certner.
01:17 - 01:21
And there was other chemist before this that created things.
01:21 - 01:24
But he was the first to isolate it itself.
01:25 - 01:28
So it is not very soluble in water or other
01:28 - 01:31
liquids, and it also has some street names, like God's
01:32 - 01:33
drug M s or morpho.
01:36 - 01:39
So some other qualities of morphine is that it weighs
01:40 - 01:46
285.34 g per mole, and it is a basic molecule
01:47 - 01:49
of 8.5 on the Ph scale.
01:50 - 01:53
And if you look at the structure over here, you
01:53 - 01:56
could see that morphine is able to donate to the
01:56 - 02:00
hydrogen. It's and it's able to accept four hydrogen and
02:01 - 02:05
has five ranks with tertiary carbon, and it's linked to
02:06 - 02:10
a tertiary amine group with two other nearby carbon atoms,
02:11 - 02:17
and it is also an odorless and solid compound.
02:23 - 02:25
So what does this drug dio?
02:25 - 02:27
I'm just so confused, but I've learned so much so
02:28 - 02:31
quickly. So this drug enters the blood stream and goes
02:31 - 02:35
deliver to get detoxified, in which only about 50% of
02:35 - 02:38
morphine will enter the central nervous system in which it
02:38 - 02:42
will then bind to the opioid receptors in the brain.
02:43 - 02:46
And then it creates these feelings of euphoria, which will
02:47 - 02:49
create the sensation of pain relief.
02:50 - 02:52
But it will not actually take the pain away.
02:52 - 02:54
It will just create this feeling within the body.
02:55 - 02:58
How are these receptors can also control other systems in
02:58 - 03:02
the body, such as respiratory functions, and digestive systems, which
03:02 - 03:03
can actually be kind of dangerous.
03:06 - 03:09
So as I mentioned here, the main goal is for
03:09 - 03:09
pain relief.
03:10 - 03:13
So as I mentioned, my doctor would give me this
03:13 - 03:15
medication because I had a surgery and I'm in a
03:15 - 03:15
lot of pain.
03:16 - 03:19
But there's other other side effects that could have happened
03:20 - 03:24
due to me taking this medication like I'm constipated, I'm
03:24 - 03:29
tired. I'm nauseous Any of these And respiratory depression can
03:29 - 03:32
be very serious as the normal respiratory rate of 12
03:32 - 03:36
to 20 can be lower and from if it's like
03:36 - 03:39
eight or 10, you can start breathing slower and then
03:39 - 03:42
eventually go into respiratory failure, and that's just not good
03:43 - 03:43
at all.
03:44 - 03:47
So why is it so dangerous, considering that morphine is
03:48 - 03:51
an opioid and there is an opioid crisis within our
03:51 - 03:52
country and globally?
03:53 - 03:56
There is a very serious issue as addiction may develop
03:57 - 04:00
and there's a tolerance that develops when you take this
04:00 - 04:03
drug as you need Mawr and Mawr to get the
04:03 - 04:07
same level of high of the drug to get the
04:07 - 04:07
same effect.
04:08 - 04:10
So if I was to be sweep prescribed by milligrams
04:11 - 04:13
and I need to keep taking this to get pain
04:13 - 04:16
relief the next time I would need 10 mg and
04:16 - 04:18
then 12, etcetera, etcetera.
04:18 - 04:21
Which creates a problem because then a kn addiction can
04:21 - 04:25
form. The most scary part about addiction to morphine is
04:26 - 04:29
that it's most commonly prescribed by doctors in which most
04:30 - 04:31
people aren't planning to get addicted.
04:32 - 04:34
Thio there painkillers after major surgery.
04:35 - 04:38
Unfortunately, sometimes it happens, which is why you have to
04:38 - 04:44
be closely monitored when you are taking morphine for pain.
04:44 - 04:49
Relief. Very long Fancy name morphine is up there.
04:49 - 04:51
I'm not going to try to say that, but the
04:51 - 04:54
boiling point is 190 degrees, and the melting point is
04:54 - 04:56
255 degrees up.
04:56 - 04:59
There's a molecule, but here is my built molecules from
05:00 - 05:05
a bunch of different angles due to the structure of
05:05 - 05:08
morphine. It can also be converted to other molecules such
05:08 - 05:11
as coding, which is another opioid by changing the alcohol
05:12 - 05:16
group Thio Meth OCS Group, which makes coding.
05:16 - 05:20
And this is just a simple methylation, and that's how
05:21 - 05:27
many molecules are converted and this gives you more drugs
05:27 - 05:28
and more variation.
05:30 - 05:31
So this is the end of my presentation.
05:32 - 05:34
I hope everybody who watched this.
05:34 - 05:37
If any of you are on here pretty watching any
05:37 - 05:39
videos, I hope you enjoyed it, Dr MacDougal.
05:39 - 05:40
Hope you enjoyed it.
05:41 - 05:44
And this is my were excited Page.
05:44 - 05:45
Right here.
05:51 - 05:51
Right here.
05:52 - 05:53
Very Christmas.
05:53 - 05:53
Happy holidays.
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