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Muscular System BIO 515 Sonya Livitz
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Sonya Livitz
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Updated Nov 11, 2020
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00:00 - 00:02
Hello. My name is Sonya Limits, and I will be
00:02 - 00:07
discussing the structure of skeletal muscles so before we dive
00:07 - 00:10
into what it is, the skeletal muscle is has many
00:10 - 00:13
different functions in the human body that is responsible for
00:13 - 00:20
locomotion. Heat, body heat production, a posture regulation of internal
00:21 - 00:26
organs, respiration as well as communication, especially between signals coming
00:26 - 00:26
from the brain.
00:27 - 00:30
But these are not the only muscles found in the
00:30 - 00:30
skeletal system.
00:31 - 00:33
In fact, we also have the smooth and cardiac muscles.
00:34 - 00:37
Smooth muscles are present in the organs, airways and blood
00:37 - 00:41
vessels, and they are involved in involuntary movement with one
00:41 - 00:41
nuclear Purcell.
00:42 - 00:42
And they're not street.
00:43 - 00:46
Not being non strategy means that it is basically not
00:46 - 00:50
banded. Cardiac muscles are present in the heart, and they're
00:50 - 00:51
involved in involuntary movement.
00:52 - 00:55
They consist of one nucleus for self, and they are
00:55 - 00:56
striated now.
00:56 - 00:59
This is similar to a skeletal muscle, because a skeletal
01:00 - 01:03
muscle is striated as well, with consistently visible banding.
01:04 - 01:07
It also has many nuclear Purcell, and it is involved
01:07 - 01:09
in voluntary movement, which is different than the other two.
01:10 - 01:12
For example, if you would like to go for a
01:12 - 01:15
walk or you would like to drink a glass of
01:15 - 01:18
water. This is voluntary, as the signals from your brain
01:18 - 01:22
are sending messages to yourselves muscles to contribute to this
01:23 - 01:24
movement in a coordinated fashion.
01:25 - 01:27
It is also a present around the bone.
01:28 - 01:34
There are over about 400 skeletal muscles in the human
01:34 - 01:37
body, which takes up a significant amount of the human
01:38 - 01:38
body weight.
01:39 - 01:41
Now this will be discussed a little bit later on
01:42 - 01:42
in the presentation.
01:43 - 01:47
But skeletal muscle is composed of muscle fibers, connective tissue
01:48 - 01:51
of blood, vessels and nerves, and these fibers are quite
01:52 - 01:54
long in form, a cylindrical shape.
01:54 - 01:58
Um, they also tend to be smaller and, um, in
01:58 - 02:02
small muscles, of course, and definitely larger in larger muscles.
02:03 - 02:06
So let's go ahead and go to the anatomy.
02:09 - 02:12
So in the anatomy skeletal muscles, air composed of bundles
02:12 - 02:15
within bundles, meaning there are many layers to this so
02:16 - 02:17
we can see it starts with the muscle, the muscle,
02:18 - 02:19
fast sickles, muscle fibers.
02:20 - 02:22
In my 05 Brill's, there are two types of my
02:23 - 02:23
own Bibles.
02:23 - 02:25
There is the Act In and Miles and miles.
02:25 - 02:29
Five bills and, um, each of the mild muscle fibers
02:29 - 02:33
are suspended side by side, Um, spaces between them are
02:33 - 02:36
filled with the circle plasm, so the circle plasm consists
02:37 - 02:40
of potassium, magnesium, phosphate and other protein enzymes.
02:42 - 02:45
Now my liberals could be found on each end of
02:46 - 02:46
the fiber.
02:47 - 02:49
They are anchored to the inner surface of circle Emma,
02:49 - 02:52
and when these mile fireballs, when they become shorter, the
02:53 - 02:53
muscle will also shorter.
02:54 - 02:58
I'll become shorter, meaning that it is contracting a ZX
02:58 - 02:59
for the circle.
02:59 - 03:01
Llama is basically the cellular membrane.
03:02 - 03:06
It protects the muscle fibers and contains Onda abundance of
03:06 - 03:10
myoglobin. What this means is that it contains many of
03:10 - 03:11
the same organelles seen in other cells.
03:11 - 03:14
And what this A ZX well is this oxygen binding
03:15 - 03:19
protein. It is also consisting of openings of the T
03:20 - 03:23
two bills, and these tubes extend into the circle plasm
03:24 - 03:25
um, at the surface.
03:25 - 03:28
The Circle plasm is known as thesis plasm of the
03:28 - 03:32
muscle fiber or the inconsistent intracellular fluid, and it holds
03:33 - 03:37
the Maya fibra ls also toe, which we will also
03:37 - 03:38
discuss a little bit.
03:38 - 03:42
Thea Mile filaments are thin, while the Myerson are thick,
03:44 - 03:46
so let's go into the structural functions.
03:47 - 03:50
So as we can see in this picture here we
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have the nuclei Thean Domizzi, um, paramecium at the museum.
03:55 - 03:58
A ZX well, a ZX, the Kalima, fast sickles and
03:58 - 03:59
blood vessels.
03:59 - 04:03
But we're going to discuss now what the top four
04:03 - 04:05
are and what their role is.
04:06 - 04:07
So, well, nuclear.
04:08 - 04:11
So the skeletal muscle has multiple new client is a
04:11 - 04:15
multi nucleus Purcell on the periphery of itself wth e
04:15 - 04:15
end. Um, easy.
04:16 - 04:18
Um, is known to be the thinner portion.
04:18 - 04:22
It surrounds each individual muscle fiber and regulates the metabolic
04:22 - 04:24
exchange between the muscles and the blood.
04:25 - 04:28
The para museum is surrounding the the bundles of these
04:29 - 04:32
fast sickles and it involved in contract tile movement.
04:34 - 04:36
As for the FM museum, it surrounds the entire muscle.
04:37 - 04:40
It protects it from damage friction that can be caused
04:40 - 04:42
with other muscles and bones.
04:43 - 04:45
My five bills we discussed consists of SAARC Amir's, and
04:46 - 04:47
it is involved in muscle contraction.
04:48 - 04:52
Um, circle Emma is basically like a barrier between the
04:52 - 04:56
internal and external environments and compartments and the physical is
04:56 - 05:00
the muscle Viber helping and determining what kind of muscle
05:00 - 05:01
movement will it be?
05:03 - 05:05
For example, are we going in a circular motion?
05:05 - 05:07
Are we going in a straight motion so it helps
05:08 - 05:14
coordinate which direction we're going Now, let's go ahead and
05:15 - 05:17
discuss wth E Sarko Plas Mick Ridiculous.
05:17 - 05:21
Um, so the circle plasma ridiculous is known to be
05:22 - 05:26
the storage of calcium islands consisting of l tubules.
05:27 - 05:31
It then functions and pushing these calcium islands out into
05:32 - 05:35
the circle Plasm So And it's important to consider how
05:35 - 05:38
the sarka plasma ridiculous is different from the end of
05:38 - 05:42
plasma Ridiculous, um which isn't responsible for the synthetic for
05:42 - 05:43
synthesizing molecules.
05:44 - 05:47
The end of class in particular, um, also consists of
05:47 - 05:50
rough and smooth, which are different, in which the rough
05:50 - 05:53
and new class in particular is bound by ribosomes and
05:53 - 05:56
stores proteins, while the smooth it doesn't is not.
05:57 - 06:01
It is more irresponsible in sword and lipid and protein
06:01 - 06:06
storage. The circle positive particular, um, also spans Sark Amir,
06:07 - 06:09
of which we can see in the diagram and thes
06:10 - 06:14
different variables that we will go through our part of
06:14 - 06:15
the composition of the circle here.
06:17 - 06:20
So as we can see here the Z, the Z
06:20 - 06:23
line on this diagram or the disc these air the
06:23 - 06:27
end of the SAARC Amir's thin acting filaments branch from
06:27 - 06:29
these Z lines towards the middle of the SAARC.
06:29 - 06:36
Amir the M line is basically the midpoint of the
06:36 - 06:39
SAARC Amir Thick Meyssan filaments will branch from the M
06:40 - 06:41
lines towards the ends of the SAARC.
06:41 - 06:46
Amir three i band is the heir of SAARC Amir,
06:46 - 06:50
where only acting filaments are present and then we see
06:50 - 06:51
here the A band.
06:51 - 06:54
Next to it is the area in the circum era
06:54 - 06:56
where the act in my sin will overlap.
06:58 - 07:01
As for our last section here, the ages own it
07:01 - 07:04
is the area of the circle near where Onley myson
07:04 - 07:05
is found to be present.
07:06 - 07:09
In addition, we should also consider the motor units.
07:10 - 07:13
Motor units are made up of muscles and it refers
07:14 - 07:16
to all of the muscle fibers that are innovated by
07:17 - 07:17
a single neuron.
07:18 - 07:21
So small motor units are involved in only a few
07:21 - 07:25
muscle fibers used for precision movement, while the large motor
07:25 - 07:29
units are involved in many muscle fibers and they are
07:29 - 07:31
integrated by a single neuron but are used in very
07:32 - 07:34
powerful movements like punching, for example.
07:35 - 07:40
Now let's go ahead, Thio muscle proteins and my vibe
07:40 - 07:46
roles Okay, So as we discussed a little bit earlier,
07:47 - 07:50
there are thin and thick mile filaments thin consist of
07:50 - 07:52
acting with nebula in attachments.
07:53 - 07:58
Um, Thio Nebula Attachment, yes, and then thick is basically
07:58 - 08:01
consisting of mice in which they have tighten attachments.
08:02 - 08:05
As we can see here in this diagram, the Titan
08:05 - 08:10
attachments or molecules are able to form elastic filaments that
08:10 - 08:13
help to connect thick filaments to the Z line.
08:13 - 08:16
As we've shown in the Sarko here, while nebula is
08:17 - 08:21
more associated with thin filaments and helps with regulating how
08:22 - 08:25
active is affected and its movement Now when we look
08:25 - 08:28
at regulatory proteins here we have triple myson and Proponent
08:29 - 08:33
triple medicine, prevents any type of contraction in muscle cells
08:33 - 08:36
and also acts as a barrier at myosin binding sites
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to active molecules.
08:38 - 08:41
Troponin, on the other hand, is involved in the attachment
08:43 - 08:44
of is also attached.
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That should be two T's.
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Sorry about that.
08:47 - 08:51
To triple myson, um, to place on acting molecules.
08:53 - 08:54
Mhm trouble.
08:54 - 09:00
Madison also is a wrapped around and acting helix, and
09:01 - 09:04
it is, um, covering active sites and the resting phase,
09:05 - 09:08
while troponin is going to be made up of three
09:08 - 09:14
protein subunits, troponin I, C and T.
09:16 - 09:18
It's also important to keep in mind that when we
09:18 - 09:22
have any type of muscle contraction, there are many different
09:22 - 09:26
changes. We have chemical, we have mechanical, thermal and electrical.
09:27 - 09:32
And in mechanical, for example, we haven't isotonic contraction, which
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basically means that there is a muscle shortening.
09:36 - 09:39
Um, but the volume of the muscle is still staying
09:39 - 09:40
the same.
09:40 - 09:43
We also happen isometric contraction, in which there is actually
09:44 - 09:46
no change in the length of the muscle.
09:47 - 09:50
Another example of a changes in thermal, which is like,
09:50 - 09:51
for example, activation heat.
09:52 - 09:56
This'll involves troponin in which energy needed for a calcium
09:57 - 10:02
influx, um, binds to the troponin and pumps out calcium
10:03 - 10:09
ions. So this is the final presentation, along with references.
10:10 - 10:11
Thank you for listening.
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