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Alzheimer's Disease
JY
by
Jeslyn Yu
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Updated Jan 21, 2022
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Chapters
00:00
Chapter 1
00:04
Chapter 2
00:38
Chapter 3
01:03
Chapter 4
01:04
Chapter 5
01:30
Chapter 6
01:32
Chapter 7
01:33
Chapter 8
02:10
Chapter 9
03:02
Chapter 10
03:04
Chapter 11
04:03
Chapter 12
04:06
Chapter 13
04:07
Chapter 14
04:51
Chapter 15
04:52
Chapter 16
Audio Transcript
Auto-generated
00:01 - 00:05
I decided to do my project on Alzheimer's. So what is it?
00:06 - 00:06
Well,
00:06 - 00:09
Alzheimer's disease is a progressive disease that affects the nervous system,
00:09 - 00:12
specifically the brain and the destruction of its neurons.
00:13 - 00:15
It begins at the areas that are responsible for memory,
00:15 - 00:18
the enter final cortex and the hippocampus
00:18 - 00:22
and slowly starts affecting language, speech and eventually simple motor skills.
00:23 - 00:26
This is not a normal part of aging and all damages are irreversible.
00:27 - 00:27
Yeah,
00:28 - 00:31
on the left is a normal brain and on the right is actually a brain
00:31 - 00:35
that has been affected by Alzheimer's and has had many of its neurons destroyed.
00:38 - 00:40
So what are the causes of Alzheimer's?
00:41 - 00:44
Well, it's not yet fully understood what causes Alzheimer's,
00:44 - 00:49
but scientists do believe that a multitude of factors are at play, such as genetics,
00:49 - 00:54
environmental factors, lifestyle, age, which can all affect the brain.
00:54 - 00:55
Over a period of time
00:55 - 00:59
buildups of protein called amyloid plaques and tau
00:59 - 01:03
in the brain are also believed to play a key role in the progression of this illness
01:04 - 01:06
and a little bit of history.
01:06 - 01:08
This is Dr. Alloy.
01:08 - 01:12
Alzheimer first he described the disease was in 1906
01:12 - 01:15
when he noticed abnormalities in a woman's brain tissue.
01:15 - 01:19
Her name was August de who had passed away due to a strange mental illness.
01:20 - 01:25
He then worked alongside Garitano pursue Winnie to study and research the illness,
01:25 - 01:29
observing three more similar cases, one of which was that of joseph f
01:33 - 01:36
right. So how was it diagnosed?
01:36 - 01:37
Well,
01:37 - 01:43
physicians can order psychiatric evaluations, memory problems problems,
01:43 - 01:45
solving problems, language tests
01:45 - 01:47
and other blood tests to be performed
01:48 - 01:53
brain scans can also be requested for, such as mris cts, pet scans
01:54 - 01:57
to support a diagnosis or to rule out other illnesses.
01:57 - 02:00
In addition, many new tests are also being created,
02:00 - 02:03
such as a blood test that can measure the levels of beta amyloid,
02:03 - 02:06
the protein that is associated with the deposits
02:06 - 02:09
that are found in patients suffering from Alzheimer's disease.
02:10 - 02:13
So what are the symptoms of these patients?
02:13 - 02:13
Well,
02:13 - 02:15
early signs of Alzheimer's disease is the
02:15 - 02:19
inability to re retain newly learned information.
02:19 - 02:22
However, not all symptoms are memory related,
02:23 - 02:25
such as the impairment of judgment and
02:25 - 02:29
reasoning changes in mood and personality wandering.
02:29 - 02:31
But as the disease develops into the moderate
02:31 - 02:36
stage symptoms can range from difficulty with language,
02:36 - 02:38
increased memory loss, hallucinations,
02:38 - 02:42
and even struggles with recognizing family.
02:42 - 02:47
And when the disease progresses far enough to be deemed late stage,
02:47 - 02:49
which goes on the complete other end of the spectrum,
02:50 - 02:53
patients may be incapable of communicating
02:53 - 02:55
and controlling their bowels slash bladder.
02:55 - 02:59
They may lose weight, suffer from seizures, have difficulty swallowing,
02:59 - 03:01
they might be asleep much more often.
03:05 - 03:07
So who is more at risk for this disease?
03:08 - 03:13
Well, Alzheimer's disease is most common for individuals who are in their mid 60s.
03:14 - 03:17
However, despite being extremely rare, early onset,
03:17 - 03:20
Alzheimer's can occur in those between 30 to 60 years old,
03:21 - 03:23
Females are also known to be more at risk
03:23 - 03:29
for Alzheimer's with them outnumbering men by over 2-1
03:30 - 03:33
countless studies and findings also indicate that african
03:33 - 03:36
americans are also more likely to be affected
03:36 - 03:37
in the United States.
03:37 - 03:41
This percentage is approximately twice as high as that of caucasians
03:42 - 03:44
Worldwide. It is estimated that one in nine
03:45 - 03:49
individuals older than 65 years old will develop Alzheimer's disease,
03:49 - 03:52
with the likelihood of these chances increasing as they age.
03:54 - 03:55
Those affected by this illness have a life
03:55 - 03:59
expectancy of about 3-11 years after diagnosis,
03:59 - 04:02
depending on the severity and progression of the illness.
04:04 - 04:04
So,
04:07 - 04:10
so what are the treatments that any patient can take?
04:11 - 04:14
Well, there's not actually a cure for alzheimer's.
04:14 - 04:14
However,
04:14 - 04:17
there are some treatments that do exist to help manage
04:17 - 04:20
the symptoms or even to slow the progression of the disease
04:20 - 04:23
Medications are most effective during early and middle
04:23 - 04:26
stages of Alzheimer's and as of June 7,
04:26 - 04:27
2021,
04:27 - 04:31
the newest medication, Raducan Umarov, was approved by the FADA.
04:32 - 04:35
This treatment reduces amyloid deposits in the brain,
04:35 - 04:38
supposedly hindering the development of alzheimer's.
04:38 - 04:41
However, this hasn't been proven to affect other symptoms,
04:41 - 04:42
but on the other hand,
04:42 - 04:45
colonist series inhibitors have been medications that
04:45 - 04:48
are solely used for patients comfort,
04:48 - 04:50
helping them cope with their symptoms
04:53 - 04:56
and with this disease comes many,
04:56 - 04:59
many health concerns and challenges for the
04:59 - 05:01
family members and the patients themselves.
05:02 - 05:06
Those who suffer from Alzheimer's disease are more likely to develop some form
05:06 - 05:10
of malnutrition due the due to the gradual decline in the ability to swallow
05:10 - 05:12
and are very prone to accidents
05:13 - 05:16
because if the illness has progressed enough,
05:16 - 05:18
it may begin affecting the cerebellum,
05:18 - 05:21
the center of balance and coordination.
05:21 - 05:25
To add, family members must also always have someone caring for the patient.
05:25 - 05:28
Do they do, to their likelihood of wandering,
05:28 - 05:30
forgetting and in turn getting lost.
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