Alzheimer's Disease

JY
by Jeslyn Yu1 view·Updated Jan 21, 2022

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  1. I decided to do my project on Alzheimer's. So what is it?
  2. Well,
  3. Alzheimer's disease is a progressive disease that affects the nervous system,
  4. specifically the brain and the destruction of its neurons.
  5. It begins at the areas that are responsible for memory,
  6. the enter final cortex and the hippocampus
  7. and slowly starts affecting language, speech and eventually simple motor skills.
  8. This is not a normal part of aging and all damages are irreversible.
  9. Yeah,
  10. on the left is a normal brain and on the right is actually a brain
  11. that has been affected by Alzheimer's and has had many of its neurons destroyed.
  12. So what are the causes of Alzheimer's?
  13. Well, it's not yet fully understood what causes Alzheimer's,
  14. but scientists do believe that a multitude of factors are at play, such as genetics,
  15. environmental factors, lifestyle, age, which can all affect the brain.
  16. Over a period of time
  17. buildups of protein called amyloid plaques and tau
  18. in the brain are also believed to play a key role in the progression of this illness
  19. and a little bit of history.
  20. This is Dr. Alloy.
  21. Alzheimer first he described the disease was in 1906
  22. when he noticed abnormalities in a woman's brain tissue.
  23. Her name was August de who had passed away due to a strange mental illness.
  24. He then worked alongside Garitano pursue Winnie to study and research the illness,
  25. observing three more similar cases, one of which was that of joseph f
  26. right. So how was it diagnosed?
  27. Well,
  28. physicians can order psychiatric evaluations, memory problems problems,
  29. solving problems, language tests
  30. and other blood tests to be performed
  31. brain scans can also be requested for, such as mris cts, pet scans
  32. to support a diagnosis or to rule out other illnesses.
  33. In addition, many new tests are also being created,
  34. such as a blood test that can measure the levels of beta amyloid,
  35. the protein that is associated with the deposits
  36. that are found in patients suffering from Alzheimer's disease.
  37. So what are the symptoms of these patients?
  38. Well,
  39. early signs of Alzheimer's disease is the
  40. inability to re retain newly learned information.
  41. However, not all symptoms are memory related,
  42. such as the impairment of judgment and
  43. reasoning changes in mood and personality wandering.
  44. But as the disease develops into the moderate
  45. stage symptoms can range from difficulty with language,
  46. increased memory loss, hallucinations,
  47. and even struggles with recognizing family.
  48. And when the disease progresses far enough to be deemed late stage,
  49. which goes on the complete other end of the spectrum,
  50. patients may be incapable of communicating
  51. and controlling their bowels slash bladder.
  52. They may lose weight, suffer from seizures, have difficulty swallowing,
  53. they might be asleep much more often.
  54. So who is more at risk for this disease?
  55. Well, Alzheimer's disease is most common for individuals who are in their mid 60s.
  56. However, despite being extremely rare, early onset,
  57. Alzheimer's can occur in those between 30 to 60 years old,
  58. Females are also known to be more at risk
  59. for Alzheimer's with them outnumbering men by over 2-1
  60. countless studies and findings also indicate that african
  61. americans are also more likely to be affected
  62. in the United States.
  63. This percentage is approximately twice as high as that of caucasians
  64. Worldwide. It is estimated that one in nine
  65. individuals older than 65 years old will develop Alzheimer's disease,
  66. with the likelihood of these chances increasing as they age.
  67. Those affected by this illness have a life
  68. expectancy of about 3-11 years after diagnosis,
  69. depending on the severity and progression of the illness.
  70. So,
  71. so what are the treatments that any patient can take?
  72. Well, there's not actually a cure for alzheimer's.
  73. However,
  74. there are some treatments that do exist to help manage
  75. the symptoms or even to slow the progression of the disease
  76. Medications are most effective during early and middle
  77. stages of Alzheimer's and as of June 7,
  78. 2021,
  79. the newest medication, Raducan Umarov, was approved by the FADA.
  80. This treatment reduces amyloid deposits in the brain,
  81. supposedly hindering the development of alzheimer's.
  82. However, this hasn't been proven to affect other symptoms,
  83. but on the other hand,
  84. colonist series inhibitors have been medications that
  85. are solely used for patients comfort,
  86. helping them cope with their symptoms
  87. and with this disease comes many,
  88. many health concerns and challenges for the
  89. family members and the patients themselves.
  90. Those who suffer from Alzheimer's disease are more likely to develop some form
  91. of malnutrition due the due to the gradual decline in the ability to swallow
  92. and are very prone to accidents
  93. because if the illness has progressed enough,
  94. it may begin affecting the cerebellum,
  95. the center of balance and coordination.
  96. To add, family members must also always have someone caring for the patient.
  97. Do they do, to their likelihood of wandering,
  98. forgetting and in turn getting lost.