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Pharmacology Review: Inhaled Nitric Oxide
MC
by
Meredith Carroll McSwain
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Updated Feb 21, 2021
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00:01 - 00:04
Hello Future and MPs today in our pharmacology review will
00:04 - 00:06
be discussing and held nitric oxide.
00:09 - 00:09
So what is in hell?
00:10 - 00:10
Nitric oxide?
00:12 - 00:14
Inhale nitric oxide, which we will now refer to as
00:15 - 00:19
I know, is indicated in neonatal with hypoxic respiratory failure
00:19 - 00:23
associated with clinical or echocardiogram thick evidence of pulmonary hypertension.
00:24 - 00:25
Also called PPH n.
00:27 - 00:30
I know it's a selective pulmonary basic dilator.
00:32 - 00:35
It relaxes vascular smooth muscle by stimulating.
00:36 - 00:40
See GMP via the gating of calcium to and potassium
00:40 - 00:44
channels by direct stimulation of potassium channels and by modulating
00:45 - 00:46
the activity of angiotensin two receptors.
00:49 - 00:53
Dilation of pulmonary vessels and well ventilated long areas redistribute
00:54 - 00:56
blood away from lung areas where beaky ratios are poor.
01:00 - 01:03
So, in a nutshell, I know decreases PPH n b
01:03 - 01:08
A pulmonary visit dilation which decreases wiki mismatch and increases
01:09 - 01:11
the partial pressure of oxygen in the arterial blood.
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