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Ultrasound Derived Fat Fraction
HH
by
Hailie Hyman
·
14 views
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Updated Jan 13, 2025
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Chapters
00:00
Chapter 1
00:18
Chapter 2
00:45
Chapter 3
01:06
Chapter 4
02:10
Chapter 5
03:01
Chapter 6
03:13
Chapter 7
03:15
Chapter 8
03:17
Chapter 9
Audio Transcript
Auto-generated
00:01 - 00:04
Hi, everyone. Today, we're gonna be talking about a more
00:05 - 00:08
innovative and newer way of diagnosing hepatic sto
00:08 - 00:13
tosis, which is also known as fatty liver disease by using ultrasound.
00:13 - 00:17
So, this technique is called ultrasound derived fat fraction.
00:18 - 00:21
So what is ultrasound, derived fat fraction?
00:21 - 00:25
So this is a newer accepted way to help diagnose fatty liver disease.
00:25 - 00:26
So,
00:26 - 00:29
we're gonna be using ultrasound waves to measure the stiffness
00:29 - 00:32
of the liver and the fat content of the liver.
00:32 - 00:34
And this helps us avoid invasive procedures
00:34 - 00:37
like liver biopsies because in health care,
00:37 - 00:38
as always,
00:38 - 00:40
we want to make sure that we are doing the least invasive
00:40 - 00:45
procedure possible as long as it is the more feasible option.
00:46 - 00:48
So I've attached a video here.
00:48 - 00:52
I cannot play it while presenting. But if you would like to watch it, feel free to do.
00:52 - 00:53
So,
00:53 - 00:56
the ultrasound tech at the Houston Medical Imaging Center is just
00:56 - 00:59
going over in more detail about what they will be doing
00:59 - 01:03
during the scan as well as giving the patient resources on
01:03 - 01:06
how to schedule an appointment to have this procedure done.
01:08 - 01:09
So for clinical application,
01:09 - 01:13
we will be using a deep abdominal transducer with a curved design.
01:14 - 01:18
And that curved design allows for a deeper penetration into the patient.
01:18 - 01:21
So that we can see those deeper structures such as the liver,
01:21 - 01:25
we will also be using 1 to 3.5 megahertz which is
01:25 - 01:29
a lower frequency. Therefore, once again, we have a
01:29 - 01:31
deeper field of view
01:31 - 01:32
with a piezo
01:32 - 01:33
ceramic element.
01:35 - 01:35
And then
01:36 - 01:42
to measure everything we'll be using a grid that contains 15 spaces.
01:42 - 01:43
So this is really good.
01:43 - 01:47
This grid is really gonna measure the attenuation coefficient in the back scatter.
01:48 - 01:52
The attenuation coefficient is really gonna help us determine um the
01:52 - 01:56
liver stiffness and then the back scatter is really gonna help
01:57 - 01:58
determine the fat content.
01:59 - 02:03
So they actually compared the ultrasound derived fat
02:04 - 02:07
fraction scans to MRI findings and they did
02:07 - 02:10
find that those they are comparable to each
02:10 - 02:13
other which leads us to our clinical study.
02:13 - 02:15
So in 2023
02:15 - 02:17
they took 100 and 22 patients
02:18 - 02:18
they went through,
02:18 - 02:21
but all the patients went through both a
02:21 - 02:25
ultrasound derived fat fraction scan and an MRI proton
02:26 - 02:27
density fat fraction scan.
02:28 - 02:29
So the results from that
02:29 - 02:33
study found that there was a positive correlation between the two,
02:33 - 02:34
meaning
02:35 - 02:39
the MRI findings agreed with the ultrasound findings as well.
02:39 - 02:41
So this really helped prove that
02:42 - 02:46
the ultrasound direct fat fraction is actually a valuable tool for helping
02:46 - 02:47
diagnose hepatic
02:47 - 02:48
citosis,
02:48 - 02:52
which is really important that we were able to compare the two and see that
02:53 - 02:59
it is accurate is is a very accurate way to help diagnose and it is a less invasive,
02:59 - 03:01
quicker, easier route to take.
03:03 - 03:04
Here are my resources.
03:04 - 03:07
Those are, I think both of those are actually case studies that you can or
03:08 - 03:09
clinical studies that you can look at.
03:10 - 03:11
Um I believe the
03:11 - 03:16
second one is actually the clinical study that we discussed right here
03:17 - 03:19
and that is all. Thank you.
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