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정철 이

on 6 January 2016

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Transcript of 방어작용

명호고 이정철(Ph.D.)
1. 생명과학 교육과정과 면역에 대한 오개념

2. 면역의 개요

3. 면역관련 실험
. germ-line 상태에서 유전자조각을 여러 개 가지고 있다
. VDJ 유전자 조각을 다양하게 재배열되어 조합된다 (combinatorial diversity).
. 재조합 시 합쳐지는 부위가 다양하다 (junctional flexibility)
. 합쳐질 때 새로운 염기들이 첨가된다 (nucleotide addition)
. 체세포 돌연변이에 의하여 V 지역의 염기배열이 바뀐다 (somatic mutation)
. heavy chain과 light chain이 서로 임의로 결합한다
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