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Off-label Drug Use
Transcript of Off-label Drug Use
The most common drugs prescribed unsafely or ineffectively off-label are antidepressants and antipsychotics. What are they? Off-label drugs are medications prescribed by doctors for purposes other than those expressly approved by the Food and Drug Administration (FDA). Drugs are most often prescribed off-label for children and pregnant women...
3 1 in 5 prescriptions in the United States are not approved by the FDA. Off-label drugs are not FDA approved, which means that they are not tested for efficacy and safety. 4 Susan Dudley, a nurse, became depressed and suicidal after taking a medication prescribed to her for nerve pain. Little did she know that that the drug was an epilepsy medication and was not approved for such use. Pharmaceutical companies must pay hundreds of millions of dollars to settle allegations of illegal marketing of drugs for off-label uses. Off-label drugs may not be covered by patient's insurance companies. The End IEVA BUTKUTE RITI CHOKSHI FF-LABEL DRUGS Why should they not be used? CLASS OF DRUG EXAMPLES OF OFF-LABEL USE anti-seizure drugs migraines, depression antidepressants chronic pain, ADHD, bipolar disorder beta-blockers (for high blood pressure and heart disease) migraines, anxiety Drugs Commonly Prescribed Off-Label Medicaid programs and other state medical support programs do not reimburse drugs prescribed to patients for off-label uses. Off-label use of drugs can create uneccesary costs both to the pharmaceutical company and the patient, putting both in DID YOU KNOW DID YOU KNOW SOLUTION Drugs should be prescribed off- label if and only if there are no other means of treatment available. In other words they can be considered as an option when none seem to be left. ...because they are routinely excluded from trials.