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Microchips Modeling Clinical Trials

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Meera Ali

on 29 May 2014

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Transcript of Microchips Modeling Clinical Trials

Microchip modeling clinical trials aim to replace the use of animals in clinical trials to more accurately test the safety and efficacy of treatment for human patients and spare the lives of countless animals typically used in testing.
Microchips Modeling Clinical Trials
who invented it
Engineering at Harvard University
Dr. Donald Ingber
Are there international applications? Is there anyway that this technology can be employed in the UAE?

What need did this technology address?

The core of the device is a tiny tube created by micro-fabrication—a technique used to make structures on the micrometer scale

Briefly discuss current innovative trends related to this

There is a lot of application for this technology, since it very recent technology and it’s published on 2013 it’s not used from the whole world.UAE may benefit from it in scientific fields where they can use it in labs to to studies for specific treatments.
some scientists use cellular models, which are often derived from human tissues. One way to obtain human cells is to use induced pluripotent stem cells, also known as iPS cells, made from adult tissues such as skin or blood which are reprogrammed into stem cells that can then become any type of cell in the body
Where this currently being used

This technology didn’t spread yet, it’s still being developed by dr.Donald Ingber and his team
Cost of technology

the cost of this technology is not identified yet, but the cost of saving animal is much more important than any thing else
Benefits

• Provide an accurate alternative to traditional animal tests
that often fail to predict human responses
• Test the safety of cosmetics
• Test the toxicity of chemicals
• Help scientists elucidate how tissues respond to new drug candidates


Improvements
It fail to maintain cell function
It does not exhibit organ-level functions
It lack predictive value


Resources
organ on a chip. (n.d.). organ on a chip. Retrieved May 21, 2014, from https://poptech.org/popcasts/donald_ingber_seren
Organs-on-Chips. (n.d.). : Wyss Institute at Harvard. Retrieved May 25, 2014, from http://wyss.harvard.edu/viewpage/460
Organs-on-Chips. (n.d.). : Wyss Institute at Harvard. Retrieved May 25, 2014, from http://wyss.harvard.edu/viewpage/461/
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