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Cancer and the

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by

Katelynn Dorn

on 22 April 2014

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Transcript of Cancer and the

tumor development
Cancer and the
Cell Cycle
Looking at how cancer develops, its treatments, and how disease is generically studied
How do these cells proliferate?
The Body's Back-up Systems
Genetics and Carcinogens
Cancer Studies
excessive proliferation of somatic cells
tumor begins to develop when cell experiences a mutation
hyperplasia- cells start growing and dividing too often
dysplasia- cells look abnormal
cell experiences another mutation and cancer is malignant
in situ cancer and invasive cancer
stages of cancer
malignant vs. benign, tumor vs. polyp
sarcoma
monoclonal or polyclonal origin?
proto-oncogenes
tumor suppressor genes
oncogenes
DNA repair system
apoptosis- the 'self-destruct button'
telomeres
If there's so much back-up, what could go wrong?
mutations in DNA repair genes
p53 protein
cells resistant to treatment- chemotherapy
telomerase active in cancer cells
asymptomatic- genotype vs. phenotype
BRCA1 gene
Melanoma
UV light
basal cells
melanin
CAT scans & radiation
necrosis- unprogrammed
leukemia
treatments
biopsy
immunotherapy and chemotherapy
remission
epidemiology
etiology
incidence rate
survival rate
morbidity rate
mortality rate
lifetime risk/relative risk
Full transcript