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Probiotic Yoghurts in UK Hospitals

Functional Microorganisms in Food
by

Alicia Julian

on 13 December 2014

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Transcript of Probiotic Yoghurts in UK Hospitals

Antibiotic treatment
Treatments
Scientific evidence
Limitations
Alicia Julian
Alexandra Waskow
Fabienne Hartmann
Wednesday, December 3, 2014
Vol XCIII, No. 311
Probiotic Yoghurts in UK hospitals
Scientific evidence
Benefits for patients and society
Objectives
Opinion
Antibiotic Associated Diarrhea (AAD)
Can Probiotics be used to prevent AAD and CDAD
Potential limits of probiotic use
Risk Factors
≥60% of hospital outbreaks
Use of antibiotic
C.difficile
infection
Clostridium difficile
15-25% cases of AAD
Enterotoxin A and B
Clostridium difficile associated Diarrhea (CDAD)
Clostridium difficile
associated Diarrhea (CDAD)
Death of 1/10 patients
1/100 infected
Economic disadvantages
Threatening illness
Studies differ on the overall outcome.
Studies have been small single-centre trials with varying quality, providing insufficient data to reliably assess of effectiveness (Allen et al. 2013).
Potential economic advantages of these treatment modalities are currently unknown (Mergenhagen et al. 2014).
Prevention with probiotics could reduce recurrent infections (CDI).
Use of probiotics could reduce the incidence of AAD and CDAD.
Since probiotics have variable efficacy, the US FDA does not currently regulate the content (Mergenhagen et al. 2014).
The use of probiotics prevents AAD and CDAD in patients taking antibiotics
CDAD
AAD
QUESTIONS?
Thank you for your attention
Treatments
Antibiotic treatment
Hospital stay
Full transcript