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Isabel Hernandez

on 26 April 2013

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Transcript of Hepatitis

"Silent Disease" An infectious disease affecting mainly the liver caused by a virus

An infected person may carry the virus for years even decades and never show symptoms (asymptomatic)

Can eventually lead to cirrhosis of the liver (intense scarring of the liver) leading to liver failure, or liver cancer The liver removes harmful substances from the blood and also makes proteins needed for blood clotting and bile acids that help with fat digestion.

Spread by blood to blood contact (usually drug use, and transfusions, sex, or unsterile medical equipment) Ashley Tierney
Brenda Gonzalez
Isabel Hernandez Hepatitis C stool blood diagnose drugs prescription symptoms virus liver type c nurses inflammation infection cancer swelling water acute tests health Rx care hospital hospital medical infectious patient treatment dead viral chronic antibodies type e contagious deadly health care doctors Hepatitis Structure
Infection Process Signs
Symptoms Acute Infection (can be resolved by the body’s immune system in 10-50% of cases)
Decreased appetite
Muscle or joint pain
Weight loss Chronic Infection Approximately 80% of exposed people develop chronic infections

About 10-30% of people develop cirrhosis (more common in males)

Of those that develop cirrhosis the risk of hepatocellular carcinoma (liver cancer) increases 20fold

Liver Cirrhosis can lead to accumulation of fluid in the abdomen, easy bruising or bleeding, enlarged veins in stomach and esophagus, jaundice (an excess of bilirubin in the blood causing yellowing of the skin and the whites of the eyes) Can be treated with medication (peginterferon and ribarvirin with boceprevir or telaprevir added in some cases)

No available vaccine Treatment 50-80% of people can be cured Most common in females Statistics An estimated 3.2 million persons in the United States have chronic Hepatitis C virus infection. Most people do not know they are infected because they don’t look or feel sick. In 2009, there were an estimated 16,000 acute Hepatitis C virus infections reported in the United States. Approximately 15,000 people die every year from Hepatitis C related liver disease. Sources Darius Moradpour, François Penin & Charles M. Rice. Replication of hepatitis C virus.
Nature Reviews Microbiology 5, 453-463 (June 2007)doi:10.1038/nrmicro1645


Viral Hepatitis Action Coalition. “Hepatitis C. Viral Hepatitis Action Coalition. N.p. 2012. Web. September 7, 2012. Www. Viralhepatitisaction.org/hepatitis-c.

Centers for Disease Control and Prevention. Hepatitis C General Information. N.p. Centers for Disease Control and Prevention, 2010. Print.

Centers for Disease Control and Prevention. MMWR August 17,2012;61(RR04):1-18.

Ryan KJ, Ray CG (editors), ed. (2004). Sherris Medical Microbiology (4th ed.). McGraw Hill. pp. 551–2. ISBN 0838585299.

Gravitz L. (2011). "A smouldering public-health crisis". Nature 474 (7350): S2-4. doi:10.1038/474S2a. PMID 21666731.

Houghton M (November 2009). "The long and winding road leading to the identification of the hepatitis C virus". Journal of Hepatology 51 (5): 939–48. doi:10.1016/j.jhep.2009.08.004. PMID 19781804.

Shors, Teri (2011-11-08). Understanding viruses (2nd ed.). Burlington, MA: Jones & Bartlett Learning. p. 535. ISBN 9780763785536.

Rosen, HR (2011-06-23). "Clinical practice. Chronic hepatitis C infection". The New England Journal of Medicine 364 (25): 2429–38. doi:10.1056/NEJMcp1006613. PMID 21696309.

Maheshwari, A; Ray S; Thuluvath PJ (2008-07-26). "Acute hepatitis C". Lancet 372 (9635): 321–32. doi:10.1016/S0140-6736(08)61116-2. PMID 18657711.

Wilkins, T; Malcolm JK; Raina D; Schade RR (2010-06-01). "Hepatitis C: diagnosis and treatment". American family physician 81 (11): 1351–7. PMID 20521755. Thank You!!
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