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Bioinformatics

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by

Nada El Jundi

on 13 May 2014

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Transcript of Bioinformatics

The -informatics in bioinformatics
Summary Questions
•What is bioinformatics?

• Can you name some of the biomedical questions studied in bioinformatics?

• Can you name some of the technical questions studied in bioinformatics?

• Why are you interested in bioinformatics?

The Bio- in Bioinformatics
Physiology/ Disease
Bioinformatics
What is Bioinformatics?
Bioinformatics: an
interdisciplinary field
that develops
and applies computer and computational technologies
to study biomedical questions.

As a technology,
bioinformatics is a powerful technology to
manage, query, and analyze big data in life sciences.



Definition
-As a technology:
As a methodology:
As a methodology,
bioinformatics is a top-down,holistic,data-driven, genome-wide, and systems approach that generates new hypotheses, finds new patterns, and discovers new functional elements.
As an interdisciplinary field
Bioinformatics
Biology
Medicine
Medical/clinical
informatics
Physics
Statistics
Mathematics
Computer
Science
Systems
Biology
Synthetic
Biology
DNA/Genome
RNA
Proteins
Molecular Networks
Cells

Genotype Phenotype
Sequence alignment
Database similarity search
Motif finding


Gene finding
Computational
& comparative
genomics
Evolution
DNA
methylation


Differential
expression
co-expression
ncRNA

Data
Management
Data Computation
Data Mining
Modeling/simulation
Protein interaction
networks
Transcriptional
regulation networks
Metabolic and
signaling networks
Network dynamics
Mass spec protein
identification
Structure prediction
Structure alignment
Virtual cell
simulations
Population genetics
Human genetics
Data Discovery
Databases
Ontologies
Meta-data
Algorithms
Software tools
Web servers
Biological
discoveries
Predictive models
Systems
simulation
Future Prospects
By Nada El Jundi
&
Rita Khattar

Thank You!
Full transcript