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Transcript of Diabetes
Is agroup of metabolic diseases that affect the body’s ability to process and use sugar for energy. therefore, recurrent or persistent hyperglycemia is present.
Deficiency of insulin or,
insensitivity of its receptor.
In type1 DM:
significant weight loss
Diabetic ketoacidosis in uncontrolled cases
In type2 DM:
Immune reaction(type1) , genetics, acromegly ,infection(CMV) ,cushing syndrome , pancreatitis and medication: glucocorticoids , interferons.
uptake of glucose from the blood into most cells
conversion of glucose to glycogen for internal storage in liver and muscle cells
protein synthesis, and fat storage.
gastric bypass surgery
Insulin therapy should be considered if the A1C is more than 8.5% after multiple therapy
Random blood glucose test
biguanide insulin sensitizer
alpha glucosidase inhibeter
increase sensitivity of insulin
sulfonylurea :incrase insulin secrtion
Type1 DM (
or "juvenile diabetes".
Type 2 DM
or "adult-onset diabetes"
Limited success in type 1 DM
Successful in many with morbid obesity and type 2 DM
A positive result should be confirmed by a repeat of any of the above methods on a different day
Usually resolves after delivery ,diet modification is the main treatment during pregnancy
Types of diabetes
can be present