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Diabetes

ppt
by

khadeeja ali

on 14 June 2013

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Transcript of Diabetes

Back Ground
Definition:
Treatment plan
Prepared by
Khadeeja Ghassan
Shurooq Hasan

Diabetes
Clinical prsentation
Diagnostic tools
Laboratory tests
Is agroup of metabolic diseases that affect the body’s ability to process and use sugar for energy. therefore, recurrent or persistent hyperglycemia is present.
Pathophysiology:

Deficiency of insulin or,
insensitivity of its receptor.
Signs
In type1 DM:
significant weight loss
polyuria
polydipsia
Diabetic ketoacidosis in uncontrolled cases
Diabetic neuropathy
In type2 DM:
lethargy
headache
Weight loss
is
not significant
Diabetic neuropathy
Hyperglcemia
Symptoms
asymptomatic
, but...
poly uria
Causes:
Immune reaction(type1) , genetics, acromegly ,infection(CMV) ,cushing syndrome , pancreatitis and medication: glucocorticoids , interferons.
uptake of glucose from the blood into most cells
conversion of glucose to glycogen for internal storage in liver and muscle cells
protein synthesis, and fat storage.
Pancreas transplants
gastric bypass surgery
Insulin therapy should be considered if the A1C is more than 8.5% after multiple therapy
Random blood glucose test
biguanide insulin sensitizer
alpha glucosidase inhibeter
Glitazone:
increase sensitivity of insulin
incretin mimetics
sulfonylurea :incrase insulin secrtion
Type1 DM (
IDDM
):
10 %
or "juvenile diabetes".
Type 2 DM
(NIDDM)
:

90%
or "adult-onset diabetes"
Gestational diabetes:

5-10 %
Limited success in type 1 DM
Successful in many with morbid obesity and type 2 DM
Lifestyle modification
Medications
Procedures
Type2 diabetes
Patient education
Type1 diabetes
DPPIV inhibitor
A positive result should be confirmed by a repeat of any of the above methods on a different day
Gestational diabetes
Usually resolves after delivery ,diet modification is the main treatment during pregnancy
Types of diabetes
can be present
Full transcript