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Gut Health

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Paul Morgyn

on 11 December 2013

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Transcript of Gut Health

Causes of Obesity
Oral Bacteria ?
Could Oral Bacteria Cause Obesity?
Probiotic Health & Obesity
Can probiotics help fight obesity?
Gut Microbiota ?
Obese Vs.
Deciding to Take Probiotics?
Always consult your physician before starting on any new supplement, vitamin, or medication!
Reasons why people begin probiotics
reoccuring yeast infections
urinary tract infections
GI sensitivity and cramps
gluten sensitivity or heavy symptoms associated with PMS
The Right Amount of Bacteria
It’s All about Balance
Approximately 80-85 % good or neutral bacteria to approximately 15-20 % harmful bacteria.
Look for supplements that contain Saccharomyces, Lactobacillus acidophilus, and bifidobacteria in the billions.
Certain brands claim zillions of CFUs (colony-forming units) per dose.
More is not always better when it comes to probiotics --- concern is that too many active organisms could produce the very symptoms we seek to alleviate.
Probiotic Guide
Will notice an improvement in symptoms in roughly two weeks.
Best probiotics include prebiotic - help the flora survive in your GI tract.
Start with foods containing bacteria.
Track changes.
If supplements are necessary, a doctor can assess which probiotics are safest and best for your particular body and condition.
Some probiotics have powerful levels of flora - will shift the acidic balance of stomach and intestines. Consult a physician, to avoid a negative interaction with medications.
May not necessarily need to take supplements to balance the bacteria of the GI tract. Foods such as yogurt, miso, and soy drinks contain live cultures and bacteria that can help solve intestinal and digestive problems.
Saliva was
collected from

313 women
with a body mass index between
27 and 32
Levels of obese group were
from a population of
232 healthy individuals
from periodontal disease studies.
Microbiological study of
salivary composition
obese women
were identified by the
of a single bacterial species
Selenomonas noxia

Study of data suggests composition of salivary bacteria changes in overweight women.
Bacteria of oral cavity is altered in disease conditions of obesity, oral cancer and dental caries.
This analysis is useful in diagnostics and potentially reflect an underlying etiology.
S. noxia
considered a disease candidate.
S. noxia
, is
Gram-negative bacteria
obligate anaerobes
found in both the mouth and the gastro-intestinal tract.
Elevated levels in the mouths of mothers giving birth to pre-term low-birthweight babies
Studies suggest
S. noxia
may be capable of triggering an inflammatory reaction and stimulating release of inflammatory mediators. Research is still ongoing between S. noxia and obesity.
Gut Bacteria From Obese Humans Adds Fat In Mice
Researchers suspected gut bacteria might play a role in human obesity.
Differences in gut bacteria in fat and lean people, could be a cause or an effect of obesity.
Those obstacles led Dr. Gordon and his colleagues to look for those rare sets of twins in which only one twin is fat.

They gave the twins’ fecal bacteria to mice that were born and reared in a sterile environment and had no bacteria of their own as a result.
Five weeks after human gut bacteria, the mice with bacteria from the fat twins had about 15 to 17 percent more body fat than those that had bacteria from thin twins.
Very Exciting News!
Fecal bacteria from lean mice transferred to fat mice resulted in fat mice getting lean!
But the opposite does not happen. No matter what the diet, bacteria from fat mice do not take over in thin mice.
This is exciting because "this is the clearest evidence to date that gut bacteria can help cause obesity.”
The next step will be to try using gut bacteria from humans to treat obesity by transplanting feces from thin people.

Human Gut Bacteria Adds
Fat To Mice
Fat Mouse
Became Lean
Why Take A Probiotic?
Healthy Digestive Tract
More than 70 percent of the body’s immune defenses are located in the intestines
Maintaining a healthy balance of intestinal bacteria
Order Today! :) The End!


Tortora Microbiology Book 11th Edition

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