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Sickle Cell Anaemia

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by

Elias Navarro

on 1 May 2014

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Transcript of Sickle Cell Anaemia

Conclusion
Sickle Cell Anemia is also known as Hemoglobin-s, and is a mutation in the haemoglobin gene. The offspring must inherent the gene from only one parent. The sickle cell gene is recessive and both parents must carry or have the gene to have offspring that show it.The mutation swaps 2 letters from the line of dna.
Genetic Chromosomal Cause
Sickle Cell Anaemia
There are no real cures to Sickle Cell Anemia, but there are effective treatments to minimize its effect on the person including ; blood transfusions, pain killers, antibiotics, and drinking fluids.

Only one test can determine if you have Sickle Cell Anemia, called a "hemoglobin electrophoresis." This accurate test determines if a person has the sickle trait or not.

Since Sickle Cell Anemia causes other diseases like kidney disease, gallstone disease, hip problems, eye problems, and leg ulcers. So these must be treated to alongside the Sickle Cell Anemia too.
Testing / Treatment
The life expectancy of a victim with Sickle Cell Anemia is very short. Most infected people die as children, from as young as 5 or 6, or as aged as 11 or 12.
Lifestyle Changes/ Influences/ Life Expectancy
New research suggests that people with this disease may now live to about 40 or 50 or even longer. New treatments are able to handle the various symptoms of Sickle Cell Anemia.

In 2009, a modified transplant of adult blood stem cells was created that could decrease the severity of Sickle Cell Anemia in 90% of affected adults.

Current Research Facts Provided
( Past 3 years)


1.Victims have a higher survival rate of malaria.

2. Most victims live in or have originated from West Africa and are Black.

3. People who have this disease do not live past childhood.

4. Sickle Cell Anemia is also known as Hemoglobin-s, and is a mutation in the haemoglobin gene.

5. People with Sickle Cell Anemia do worse on brain tests than non victims.

6. There are two types of Sickle Cell disease Hbss and Hbsc. Hbss is when the person has two mutated genes "s" and "s" while Hbsc people have one mutated gene "s" and one normal gene "c".

7. Hispanics are also capable of inheriting this mutation along with Africans.

8. Stem cell transplants may offer a cure for a small number of people but may cause serious side effects if they dont work including death.

9. Blood transfusions are a type of treatment for Sickle Cell Anemia.

10. Research says that the life expectancy is increasing for victims.

11. Although this is a sometimes fatal disease not enough research is being done to find a cue

12. One in every 500 blacks have the disease.

13. One in every 36,000 hispanics carry the disease.

14. Sickle cells clog the veins and arteries because of their abnormal shape

15. Children with Sickle cell Anemia have high risk of stroke so they get blood transfusions to lessen the risk.
Sickle Cell Anemia Facts
Should black athletes and people in the service be tested? - "In military personnel, they found a 30-fold increase in the risk of sudden death for people with sickle cell trait who were in boot camps," - Dr. Robert Dimeff

But, according to the National Athletic Trainers Association "The top four causes of non-traumatic sports death, in order of occurrence,are heart conditions, heatstroke, sickle cell trait complications and asthma."

This is in debate because if Sickle Cell trait is being tested should the other causes of sudden death be tested too?
Debate/Ethics of Topics
"What Is Sickle Cell Anemia?." - NHLBI, NIH. National Institutes of Health, n.d. Web. 22 Apr. 2014.

"Sickle cell anemia: MedlinePlus Medical Encyclopedia." <i>U.S National Library of Medicine</i>. U.S. National Library of Medicine, n.d. Web. 22 Apr. 2014.

"Sickle cell anemia." N.p., n.d. Web. 22 Apr. 2014.

"Latest Sickle Cell Research | NIH MedlinePlus the Magazine." <i>U.S National Library of Medicine</i>. U.S. National Library of Medicine, n.d. Web. 22 Apr. 2014.

"Debate Heats Up Over Screening Athletes for Sickle Cell Trait." <i>Consumer HealthDay</i>. N.p., n.d. Web. 22 Apr. 2014.
Works Cited
Sickle Cell Anemia is an
inherited genetic mutation where a majority of the infected person's red blood cells are morphed into a sickle like
shape. This can cause blood cloggage as sickled cells dont flow as well as regular The symptoms include -
fever, joint and abdominal pain,and jaundice.

What is Sickle Cell Anemia?
By Carlson Cheng and Julian Wahl
Victims need constant hospital care to recieve treatments as needed.
In conclusion, Sickle Cell Anemia is a severe mutation as it has many symptoms that are diseases themselves. Thankfully, due to reseach of Sickle Cell Anemia the lifestyles of victims are not changed as much as they should be.
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