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Genetics Timeline-Extra Credit

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Amari Suskin-Sperry

on 30 November 2012

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Transcript of Genetics Timeline-Extra Credit

Uncovering DNA Genetic Timeline 1928- Frederick Griffith 1957- Fraenkel-Conrat and Singer Proved that genes can be transferred via conjugation. He showed this by using heat-killed virulent and live non-virulent bacteria. Proved that within DNA, the ratio of A:T was 1 as was the ratio of G:C. To show this he used species-specific nuclei acid compositions. 1950- Erwin Chargaff Found that genes can be transferred via transduction. They discovered this when they separated auxotrophic bacteria with a filter. 1951- Lederberg and Zinder Used radiolabled bacteriophage to show that DNA functions as the genetic material. 1952- Hershey and Chase Found that RNA functions as a genetic material. They proved this by using hybrid TMV. 1944- Avery, MaCleod & McCarty Found that the purified transforming principle in Griffith experiment was DNA. 1946- Lederberg and Tatum Put auxotrophic bacteria in physical contact of each other and found that genes can be transferred via conjugation. After reviewing their X-ray crystallography, they found that DNA is in a double helical structure. 1951- Fanklin and Gosling 1953- Watson and Crick Proved, with primitive molecular models, that DNA is a double stranded helix with complementary base pairing. http://www.uic.edu/classes/bios/bios100/lectures/hershey-chase.gif http://www.angelfire.com/dc/apgenetics/fred.grif.4.jpg http://academic.pgcc.edu/~kroberts/Lecture/Chapter%207/07-32b_ConjugationArt_L.jpg http://2.bp.blogspot.com/_T-ZaNqYdy-Q/SfGKOlLgfDI/AAAAAAAAAC0/Cxb49RRlTX8/s400/chargaffs_rule2.png http://scienceblogs.com/bioephemera/wp-content/blogs.dir/263/files/2012/04/i-81b949b2f5e0fdbb3250d9a42ba4eda2-dna.jpg http://www.biologie.uni-hamburg.de/b-online/library/bio201/hersheychase.gif http://www.chemheritage.org/Images/Main-Images-250x290/Discover/Themes/Biomolecules/watson-crick1.jpg Amari Suskin-Sperry
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