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Alzheimer Disease

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Zohra D

on 27 January 2013

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Transcript of Alzheimer Disease

By: Shivani Patel, Juhi Dhuka, and Zohra Dharamshi Alzheimer Disease What is Alzheimer Disease? Brain disease that causes gradual loss of memory and it often becomes hard to judge actions. Symptoms Restlessness.
Loss of language skills.
Personality and behavioral changes.
Trouble naming people and objects.
Spatial orientation.
Need help with dressing, eating, and personal care. Genes related to Alzheimer Disease Caused by gene mutations.
When these genes are altered, amyloid beta peptide is produced which builds up to form amyloid plaques.
People who have Down Syndrome may be at higher risk than other people to get Alzheimer disease. How Do People Inherit Alzheimer Disease? Most of the time, one affected parent with Alzheimer disease passes on the altered gene to it's child.

People who inherit one copy of the APOE e4 allele have a high chance of getting Alzheimer disease, but people who inherit two copies of the allele have an even higher chance of inheriting the disease.

People with Alzheimer disease don't necessarily have to have the APOE e4 allele, and not all people who have the allele will develop the disease. Usually appears in people older than age 65. Affected individual usually survive 8-10 years, but the course of the disease can range from 1-25 years. How common is Alzheimer Disease? Alzheimer disease currently affects an estimated 2.4 million to 4.5 million Americans. Down Syndrome and Alzheimer Down syndrome occurs when there are three copies of genes found on chromosome 21. These individuals can develop Alzheimer after the age of 40. Stage Five Stage One Stage Three Individuals carry the predictive gene but have no symptoms. Stage Two Person is aware of the decline of mental functions. Person experiences difficulty in performing mental skills. Stage Four Person requires assistance with common tasks. Person needs assistance in making personal everyday decisions. (What to eat, wear, etc.) Stage Six Person requires assistance dressing, bathing, and using the toilet. Stage Seven Person cannot communicate much or walk. Person experiences a lack of muscle control and cannot smile or hold up his/her heads. Testing for Alzheimer One in eight older Americans has Alzheimer's disease There is no single test that proves a person has Alzheimer's. A diagnosis is made through a complete assessment that considers all possible causes.
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