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Necrotizing Fascitis

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jake holguin

on 13 May 2010

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Transcript of Necrotizing Fascitis

Necrotizing Fasciitis What is it ???
Flesh eating bacteria
a rare infection of the deep layers of skin & hypodermis
Diarrhea & Vomiting
Tissue becomes swollen within several ours
Pain of the skin
May have fever & appear ill

Surgery is required to remove the infected tissue & prevent spreading
Antibiotics can be taken such as penicillin, vancomycin, and clindamycin. How it progresses over time :
Lack of treatment
If the infection spreads damaging more tissue

This disease has been around for centuries and was common during the civil war. It is also common in military hospitals and war-torn areas.
It was thought to be caused by a bacteria that started in China called hemolytic streptococcus.
Other terms used to describe this condition include streptococcal gangrene, hospital gangrene, necrotizing erysipelas, and suppurative fasciitis.
Epidemiology :
If diagnosed with the disease it is possible to spread within sevaral hours and days. It is spread If an infected person has direct contact with a non infected person with mucus from the nose or throat of persons who are infected or through contact with infected wounds or sores on the skin.There are 500 to 1500 cases per year and 20% of people infected with the disease die. The disease affects populations of people with weak immune systems and poor health habits. You can find the disease around open wounds or people with weak immune systems. Impacts on Body Systems

• Digestive System
-Causes Nausea and Diarrhea almost immediately after the disease is contracted
• Integumentary System
• - Pain, swelling, warmth, or redness, Red streaks leading from a wound, Pus draining from a wound, swollen lymph nodes in your neck, armpits, or groin.
• Cardiovascular System
-When the bacterium destroys the organs it also destroys arteries and blood vessels causing a lot of internal bleeding.
• Excretory/Reproductive System
-Pus can drain through the groin and the bacterium can potentially destroy the reproductive organs.
• Nervous System
-The bacterium breaks down nerves and makes the whole infected area very painful and sensitive.
• Endocrine System
- Can affect Kidneys by the bacterium destroying them or could cause kidney failure due to it filling with pus.
Long-Term Prognosis

Long term effects of Necrotizing Fasciitis are the permanent deterioration of the tissue inside of the body. It can also lead to gangrene and other flesh deteriorating diseases, along with amputation. Immune System Reaction

The bacterium from Necrotizing Fasciitis doesn’t exactly eat the skin. They cause the destruction of skin and muscle by releasing toxin (virulence factors), which include streptococcal pyogenic exotoxins. S. pyogenes produces an exotoxin known as a superantigen. This toxin is capable of activating T-cells non-specifically, which causes the overproduction of cytokines. By: Antonia Tyson & Taylor Thompson
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