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SURVIVAL OF THE SICKEST

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by

Shelby Thacker

on 14 November 2014

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Transcript of SURVIVAL OF THE SICKEST

"jumping genes" - whole sequences of DNA that moved from one place to another during times of enviornmental stress.
Scientists have discovered that DNA can be modified in more than random mutations.
Jumping genes perform a "cut and paste".
Large portions of our junk DNA are made of jumping genes.
Retroviruses are made up of RNA, can be written into DNA.
HIV is a retrovirus and the "drug cocktail" therapy used to combat HIV is aimed at stopping the enzyme that helps retroviruses that are apart of DNA called HERVS, human endogenus retroviruses, play a number of roles and produces a healthy placenta.
People with favism cannot clear out teh free radicals produced by fava beans because of genetic deficiency.
The free radicals attack red blood cells.
These same people end up being more resistant to malaria.
Malarial Parasites find the red blood cells of people with favism not to their liking.
Chapter 6: Jump into the Gene Pool
Chapter 4: He, Bud, Can You Do Me a Fava?
Chapter 8: That's Life:
Why You and Your iPod Must Die
Chapter 7-
Methyl Madness: Road to the Final Phenotype
Survival of the Sickest
Survival of the Sickest Summary
The focus of the book is to provide the viewers a glimpse into evolutionary biology. It helps the readers understand that there is a connection between various diseases, genetics and environmental factors that still remain undiscovered and that medical conditions that are diseases were the result of Evolutionary changes. The book talks about diseases and situations such as Hemochromatosis, Diabetes, Malaria, Parasitic Experiences, Mutating DNA, Genetic Suprression, and Childhood Obesity.
Summary
Savannah Theory: a male-based theory that explains why humans walk upright and have little hair.
Aquatic Ape Theory: discovered by Elaine Morgan, who challenged the Savannah Theory with her Aquatic Ape Theory, which she believed a small population lived in and around water in what is now Ethiopia.
POINTS THAT FAVOR AQUATIC APE THEORY:
Humans are the only land animals with fat attached to the skin (hippos and sealions)
Walking upright helps in venturing into deeper water and so this how bipedalism began.
The ability to survive in both land and water environments has tremendous survival benefits against predators.
The extra fat on babies helps keep them afloat.
We have downward facing nostrils, which allows us to dive.
Newborns don't start breathing until air reaches their face, which makes birthing in water safe and easier for the mother.
Newborns reflexively hold their breath, but make rhythmic movements that propel them through water, makes sense in Aquatic Ape Theory than the Savannah Theory.
Epigenetics- Concerned with how children can inherit and express seemingly new traits from their parents without changes in the underlying DNA.

Basically, a woman's enviornment and dietary habits can cause DNA methylation in their child.

Methylaton- When a compound binds to a gene and changes the way that gene expresses itself.
Example- Agouti mice are known for being fat and yellow. Scientists gave a pregnant agouti mouse better prenatal care, the baby came out thin and brown.
Madison Schmidt
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Full transcript