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Transcript of Fentanyl
Mechanism of action: opioid mu receptor agonist
First synthesized by Janssen Pharmaceuticals in the 1950s
Up to 100 times more potent than morphine
Found in many different forms including patches, tablets, lozenges, nasal sprays, and injections
Highly addictive Background First appeared around 2002 during a heroin shortage
(As of 2012) More deaths related to overdose than road deaths
Higher levels of crime and HIV
Produced in clandestine laboratories in Russia and smuggled in illegally
Completely replaced heroin on the Estonian market because heroin was no competition to fentanyl
Overdose deaths the highest of all European nations By: Emily Hampton 136 Australian's have died from overdose in last 12 years (2013)
2/3 had never been prescribed the drug
95% of fentanyl prescriptions were for patch form, but 2/3 of deaths were from injections
The abuse is worse in regional areas "China White" outbreaks
13 deaths in 1980 in Southern California from what was believed to be "synthetic heroin"
Then found to contain a derivative of fentanyl
Deaths from heroin users continued to grow
China White contained 50-80 mcg on average
Another group of users were found taking up to 50 times these amounts and still living
Fentanyl or the combination with heroin that was killing victims? Increased abuse because of stricter controls on Oxycontin
253 deaths from 2009-2011
Also resulted in higher crime rates
Could potentially stop letting the province pay for prescriptions Works Cited
"DrugBank: Fentanyl (DB00813)." DrugBank. N.p., n.d. Web. 12 Apr. 2013. <http://www.drugbank.ca/drugs/DB00813>.
"Fentanyl's deadly arrival in Ottawa - Ottawa - CBC News." CBC.ca - Canadian News Sports Entertainment Kids Docs Radio TV. N.p., n.d. Web. 12 Apr. 2013. <http://www.cbc.ca/news/canada/ottawa/story/2013/01/11/f-ottawa-the-rise-of-fentanyl.html>.
Hagan, Kate. "Painkiller abuse takes heavy toll." Canberra Times - For local Canberra News, World News & Breaking News in ACT, Australia. N.p., n.d. Web. 12 Apr. 2013. <http://www.canberratimes.com.au/national/painkiller-abuse-takes-heavy-toll-20130321-2gijd.html>.
Hunt, Nevil. "Fentanyl dose, availability may be cut: expert, Drug abused locally could be de-listed by province - News - By Nevil Hunt Nepean/Barrhaven Local Community News." Nepean/Barrhaven Local Community News. N.p., n.d. Web. 12 Apr. 2013. <http://www.emcbarrhaven.ca/20130404/news/Fentanyl+dose,+availability+may+be+cut%3A+expert,+Drug+abused+locally+could+be+de-listed+by+province>.
Shafer, J. (1985). Designer Drugs. Science 85. Retrieved February 26, 2013 from http://www.jackshafer.com/magazine_work/20091128_designer_drugs.php.
Wilson, Sam. "BBC News - Synthetic drug fentanyl causes overdose boom in Estonia." BBC - Homepage. N.p., n.d. Web. 12 Apr. 2013. <http://www.bbc.co.uk/news/world-europe-17524945>.