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Overview of Adaptive Immune Response

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by

Mary Frances Ypma-Wong

on 16 September 2011

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Transcript of Overview of Adaptive Immune Response

Adaptive Immunity in Humans:
Humoral and Cell-Mediated Responses

Learning Objectives

1. List the features of an antigen.

2. Outline the origins of B and T lymphocytes.

3. Describe the dual nature of the adaptive immune response:

Humoral and Cell-Mediated





4. Be able to draw the structure of a typical antibody molecule.

5. Explain the benefits of clonal selection and expansion of B lymphocytes, especially in immunization.

6. Describe the five consequences of antibody binding.

7. Detail the activation of B cells during the humoral response.

8. Detail the activation of T cells during the cell-mediated response.

9. Compare the four categories of adaptive immunities. 1. Describe the features of an antigen 2. Outline the origins of B and T lymphocytes. 3.Describe the dual nature of the adaptive immune reponse 4. Be able to draw the structure of a typical antibody molecule. 7. Detail the activation of B cells during the humoral response 9. Describe the four categories of adaptive immunities Specific Memory Memory of a lifetime 8. Detail the activation of T cells B Cell Activation T cell activation 5. Clonal selection and expansion of B lymphocyte 6. Describe the five consequences of antibody binding The DNA of B and T cells been rearranged so that there are millions of different T and B cells.
Each cell expresses the respective antigen binding receptor (TCR, BCR) on its surface, waiting to be bound and activated.
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