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Hemophilia By Elise Miles

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elise miles

on 19 September 2014

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Transcript of Hemophilia By Elise Miles

What is Hemophilia?
Hemophilia is a rare bleeding disorder in which the blood does not clot normally.
Who does Hemophilia affect?
Hemophilia is an inherited disease meaning that if both of your parents are carriers of Hemophilia then you can receive the mutated gene. Hemophilia is a mutation of the X chromosome which means that while women can be carriers of the gene, only men can have Hemophilia. However, there are rare cases where females can be carriers with symptoms of Hemophilia. Hemophilia affects 1 in 5,000 males and it currently affects approximately 20,000 males in the United States alone.
• Frequent and hard to stop nose-bleeds
• Bloody urine or stool
• Bleeding in the head after difficult child birth
• Bleeding after shots and vaccinations
• Bleeding after circumcision
• Uncontrollable bleeding of the mouth and gums after losing a tooth
• Bruising of the skin or muscle and soft tissue causing a buildup of blood
• Bleeding of the joints causing swelling and pain in the joints

How does Hemophilia disrupt homeostasis on the cellular level?
Blood contains a lot of proteins that help the blood clot. Clotting of the blood is vital because it stops bleeding from internal and external injuries such as a scrapped knee or a blood vessel that has burst. People who have hemophilia lack the proteins necessary to allow the blood to clot. There are several types of Hemophilia that range in severity. The severity of Hemophilia pertains to how much of clotting factor 8 or clotting factor 9 present in blood.

What are the treatments for Hemophilia?
Hemophilia can be managed but not treated. The most popular treatment for Hemophilia is replacing the missing clotting factors. They do this by injecting the factor intravenously. By implementing regular factor infusions most bleeding episodes will stop and people with Hemophilia can live a normal, healthy life. However, approximately 15-20% of people with Hemophilia develop an antibody or inhibitor that causes the body to refuse the factor. They require more intensive care to manage their bleeding episodes and require more types of factor.
By Elise Miles
What are the signs and symptoms of Hemophilia?
Citations And Images Used
"Facts." Centers for Disease Control and Prevention. Centers for Disease Control and Prevention, 26 Aug. 2014. Web. 18 Sept. 2014.






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