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Synthetic Biology

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Zack Larmer

on 27 March 2013

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Transcript of Synthetic Biology

AGAINST Synthetic Biology promotes dangerous pathogens. Synthetic Biology makes challenges in rDNA technologies harder. There is too much money involved with the production of Synthetic Biology.
As of 2007, 2 weeks of synthesis of a 1000 BP gene cost $800. If a bioreactor were to leak, microbes and bacteria could start eating away at everything.
Biological warfare could become a huge problem. The Synbio companies may not keep the public informed of new developments at all times.
Zack Larmer
Jordan Sharp
Cameron Zurmuhl Synthetic Biology What is it? taking foreign
DNA from one organism and introducing it into a different organism Give me an example. In Japan, genetically engineered fluorescent bacteria were organized to shape Mario.
creating synthetic fuels
breaking down toxic substances
Microbes that find and destroy tumors
Bacteria that can transmit electricity
Artimisinin: a treatment for Malaria moral/ethical issues. Citations Glossary History of Synthetic Biology A disease caused by parasites infecting the human bloodstream. It is most often passed by infected mosquitoes biting humans. Malaria can also be transmitted from mother to her unborn child or through a blood transfusion. There are about 300-500 cases each year and about 1 million deaths. MALARIA We don’t yet have the capabilities to produce many new organisms, as many people believe. We are still not quite sure of how it works. A measurement to find the age of something. A formula for finding a close measurement of BP is to subtract the current date from 1950. A gene that is at 1000 BP has been in existence since year 950 AD.
BP PATHOGEN A bacteria, virus, or other microorganism that can cause disease. Prof. Dr. Mikhail Zeppezauer: working in Germany. SYNTHETIC not natural; artificial Synthetic Biology fully functioning organisms RESULT How Old Is It? The actual field is about 10
years old. The Beginning In 1828, German scientist Friedrich Wöhler mixed ammonium chloride with silver isocyanate to create urea, without knowing it, this German chemist could of stumbled on the first known case of synthetic biology. Contributors Craig Venter: successfully created a new form of bacteria, pioneering the industry in the early 2000s. Kartik Madiraju, a high school student who used bacteria to transmit electricity Synbio projects in Europe Dr. Alexander Prikhodko: working in a laboratory in Russia & Mr. Andrew Bacon: working in Great Britain & PRO CON Governments seeking the use of Synthetic Biology exhibit possibilities of terrorism

Biowar Why must everybody have the outlook on “making life better” if it is already acceptable today? We haven't discovered enough to make biological weapons yet, and they are not expected in the near future. "Our goals in studying and making biology
have already been achieved (Cloning, gene therapy, genetically modified foods etc.) ,and it has become a waste of money to continue this research." Synthetic Biology promotes new cures. Because it is a new scientific field, there is not a capability for bioterrorism with new organisms. SYNBIOSAFE is monitoring safety concerns. There are guidelines that are being used to prevent synthetic viruses and bacteria from bringing harm to humans. Scientists say they will install kill switches in synthesized organisms in case they escape and run amok. FOR The Debate Next generation biofuels, based on Synbio, will utilize previously low-valued surplus. AMMONIUM CHLORIDE a white crystallized drug that is moderately acidic and soluble in water http://www.sciencemag.org/content/333/6047/1235
http://www.britannica.com/EBchecked/topic/1692043/synthetic-biology
http://www.pbs.org/wgbh/nova/next/tech/why-synthetic-biology-is-the-field-of-the-future/
http://www.sciencemag.org/content/333/6047/1238.summary
http://www.nationmaster.com/encyclopedia/Synthetic-biology#Human_practices:_Emerging_social.2C_ethical.2C_legal_challenges
http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001646/
http://www.popsci.com/science/article/2009-12/japanese-create-fluorescent-mario-genetically-engineered-bacteria
http://www.newscientist.com/article/mg21428684.800-lets-get-real-on-synthetic-biology.html
http://blogs.ei.columbia.edu/2011/07/08/synthetic-biology-creating-new-forms-of-life/
http://www.telegraph.co.uk/science/science-news/3310890/Malicious-use-of-synthetic-viruses-feared.html http://www.newscientist.com/article/mg21428684.800-lets-get-real-on-synthetic-biology.html
http://www.britannica.com/EBchecked/topic/1692043/synthetic-biology/296881/History-of-synthetic-biology
http://www.wired.com/wiredscience/2010/06/synthetic-biology-money/
http://www.synbio-pharma.com/issledovaniia-i-razrabotki/rd-facilities
http://www.popsci.com/science/article/2011-01/princeton-researchers-construct-wholly-artificial-proteins-can-sustain-cell-life Opinions of the Debates Cameron's Opinion Zack's Opinion Jordan's Opinion Synthetic Biology makes people think of "expanding" outside the realm of natural life. Science... The Future... The main product of protein metabolism that breaks down nitrogen in mammals and is excreted in urine. UREA
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