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Longevity Aegon 2016 04
Transcript of Longevity Aegon 2016 04
for your attention
These are my opinions and are not intended to reflect the views of any group or organization with which I may be affiliated.
Biotech Chair: Singularity U
Co-Founder: Playtpus Project
Co-Founder & Chief Architect: BioCurious
Principal: Exponential Biosciences
Current Research Areas:
Therapeutic Genetic Engineering
Low Cost Access to Biotech Tools
Cancer Dx and Treatment
The Business of Longevity
One More Thing...
from being in
an exponential business
Find an exponential trend,
A prototype beats a plan
Product Development Process (PDP)
18 month development cycle,
9 month market life
make new & rev old products
core team leaders involved from start
manage technical and business risk
Nothing fades faster than last year's technology
Add a specialty
Be half of a team
Assemble a varied team
Develop internal people
Design Your Own Major?
Makes vaccines using mRNA from diseases
"Vaccinated with information"
Gates Foundation invests $57M
"Cellular scissors chop up HIV virus"
Nature Communications "Use of the CRISPR/Cas9 system as an intracellular defense against HIV-1 infection in human cells", Liao et al
23andMe and Apple
enter drug research business
"crowd-sourced clinical trials"
- Parkinson's Disease
- Breast Cancer
Enrolled 7400+ people in 24 hours.
Previous largest study was 1700.
Live Longer or Die Trying
People who never got:
Q: Secret to live a long time?
A: Pick good parents!
Implants are Easy and Coming Soon
Command & Control
Biosensing implants in development
temperature, blood pressure, ECG
heart attack, stroke early warning
Limit at 120, for a while
Proposal: Longevity Lab
Pensions & Advanced Health Accounts
It Varies, by Disease & Country
Life Expectancy +29.2 years
Deaths in ages 0-5
Death Be Not Proud, Part 1
Death is not a Democrat
I intend to live forever. So far, so good. ~Steven Wright
Life Expectancy +25
Deaths in ages 85-110
Death Be Not Proud, Part 2
Genome Project Dividend
Worldwide Infectious Disease
Traumatic Brain Injury
Macular Degeneration, Cataracts
Heart Attack Repair
Heart Valve Replacement
Joint Injury Repair
Cancer Innate Immunity
Copyright 2016, Raymond McCauley, All Rights Reserved
Adapted from Paul Knopfler, Stem Cells, An Insider's Guide
Spinal Cord Regeneration
Stem cell therapy
Death Be Not Proud, Part 3
Organ Preservation Alliance
People and Nations
More Education Time
Financial Behavior Change
Underestimate Savings Need
Health Care Cost Increase
Longevity Escape Velocity
+ 3.0 months / year
+ 2.5 months / year
Add Survival Curves, years to different death thing
Add references to money pieces (& add money figures)
SHow how actuarial curves are always wrong
Call new tech "deal breakers" "disruptions"
Discuss Longevity Escape Velocity as a Moore's law -- driven by economics
Ray Kurzweil prediction: +1 year / year by 2029
- 19 April 2016, "Reinvent Yourself: The Playboy Interview with Ray Kurzweil"