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Clinical Pathology II Review I

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by

Dianne Kirk

on 18 September 2014

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Transcript of Clinical Pathology II Review I

Clinical Pathology Review
Part I
An inclusion body seen due to hormones
Acanthocytes are seen in:
hyposegmentation is seen in:
NRBC's are normally seen in:
Ovalocytes are normal in:
Kurloff Body
Seen in ?
Male rats
Pot belly pigs
chinchillas
birds, reptiles, fish
camels, llamas
Polychromasia is common in:
Rats
Sickle Cells are seen in:
White tailed deer
What is present in a regenerative anemia?
nrbc's
polychromasia
macrocytosis
retics increased
anisocytosis
What may cause a nonregenerative anemia
lymphoma, (BM dz)
systemic infection,
hypoestrogenism
basophilic stippling in an avian sample is most indicative of:
A nregenerative anemia
How is a WBC count accomplished on an avian sample ?
phyloine B stain or eosinophil unopette
Mycoplasma canis
Bovine
Anaplasma marginale
Bovine
babesia bigemina
dz?
Texas fever,
Redwater fever,
Cattle tick fever
Feline
cytauxoon felis
dirofilaria vs. dipetalonema
Avian blood
leukocytozoon
Parasite that appears as a chain of small cocci in rbc - canine
Parasites
Feline
dz?
Feline infectious anemia
Spread by?
Rhipicephalus (Boophilus) annulatus
Also known as the Blue cattle tick, Texas cattle fever tick, cattle fever tick
Pathogenesis: Babesia bigemina, Babesia bovis, Anaplasma marginale
equine
babesia equi
dz?
piroplasmosis
canine
ehrlichia canis
canine
Trypanosoma cruzi
dz?
Chagas disease
dz?
tropical pancytopenia
head tapered
tail hooked
movement directional
size >310 um
sparse
dirofilaria vs. dipetalonema
head tapered
tail hooked
movement directional
size >310 um
sparse
Bone Marrow Examination
What results are obtained from a BM sample?
Cellularity - % fat normal
Megakaryocytes
M:E ratio - normal ?
Orderliness of maturation - ?
Macrophages
Hemosiderin - represents ?
Microorganisms
What samples are collected?
Aspirate and Biopsy
Anticoagulant/preservative?
Aspirate -
Heparin for cytogenetics
EDTA for morphology
Bx - Formalin
50% fat in adults
ME ratio 0.5 to 3 : 1
orderliness -
inverted pyramid = more mature to immature
hemosiderin = iron stores
reversible stem cell injuries
drugs, viruses, toxicities
irreversible stem cell injury
FeLV
Stem cell damage
Myeloid cell maturation

Include criteria for ID
Myeloblast
Fine chromatin
nucleoli
scant cytoplasm
Promyelocyte
Fine chromatin
Primary Granuoles
nucleoli

Myelocyte
Secondary granuoles
Round nucleus
Metamyelocyte
Pink granuoles
indented nucleus
Banded neutrophil
pink granuoles
banded nucleus
Segmented nucleus
pink granuoles
segmented nucleus
Hypersegmented nucleus
pink granuoles
>5 lobes
Hyposegmented Neutrophils
Full transcript