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GSP Bio 3 Future of Food McCauley v3

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Raymond McCauley

on 26 February 2018

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Transcript of GSP Bio 3 Future of Food McCauley v3

Agriculture & Food Applications
good preview
of things to come
Biomimetics / Packaging
Nutrigenomics
environmental impact
food security
Hyperlocal Farming
Vertical Farming
hyperorganic, hyperlocal
pesticide & herbicide free
Fiesta Hypermart, Houston, Texas, 1991
10,000+ sq ft hydroponic produce dept
Houston's biggest tourist attraction
Backed by NASA CELSS research group
6 months
700 000 meals sold
$2+M revenues
biodegradable & delicious
protein-based packaging
Bob's, Brazil
just the beginning...
Making Leather and Meat Better
Courtesy Ruby Gadelrab, Invitae
Personalized & Functional Foods
Now, Near, Next
Trends: Urbanization, Food Security 3.0
Trends: DNA, Ubi-Sensors
Trends: Disruption, Eco Foods, Food Security 3.0
yogurt = finger food
WikiFood, WikiPearl
Dave Edwards, Harvard bioengineer
Trends: Eco Foods, Food Security 3.0
Livestock Genotyping
trait prediction
breed, pedigree, parentage
identification
outbreak traceability
Genus PLC
Jerry Thompson, COO
David Hunt,
Co-Founder
Trends: Big Data, Ubi-Sensors, Robotics, DNA, Microbiomics
Digitizing Agriculture
DNA
Sequencing
2020
=
+
2001
=
ApE = A Plasmid Editor
Rise of the
Biotech
Garage
Inventor
bioprinter project
OpenPCR
$599 DNA Copy Machine
+
Cow-Free
Milk & Cheese
Genetic
Engineering
Software Development
=
But not today...
2015
=
A hackerspace for biotech

First biohacker lab in the world

Committed to making biotech
accessible, affordable, and open to everyone

Located in Sunnyvale, California

501c3 all-volunteer community lab, supported by monthly memberships and classes
We teach
classes...
We mentor the
next generation
of scientists
and technologists
We build
community
BioCurious/FBI
Joint Conference on
Biohacking
June 12-16, 2012
We are
everywhere
...
currently tracking
23 community labs
200+ individual labs
on 6 continents
Boston
Paris
San Diego
Seattle
Oakland
Portland
Manchester UK
Biologigaragen
Biospace
Victoria, Canada
Denmark
Switzerland
BGI/DIY
Shenzhen
BioGarage
Tokyo
Brooklyn
SYNBIO
Brasil
$200 qPCR
20 min sample prep + readout
Introduction
Demo...
Optical
Silicon
Molecular
Genetic/Bio
Quantum
Photospectrometry
Hyper- and multispectral
Molecular nanosensors
next
modes
trends
Cheaper
Ubiquitous
Miniaturized
Networked
Multiphysics
sensors
sensors
homes
kitchens
phones
appliances
families
in
sensors
farms
distribution
stores
suppliers
industry
in
Best Taste
Freshness
Safety
Tracking
uses
What kinds of measurements?
Freshness / Ripeness
Flavor
Nutrition
bacteria
adulteration
allergens
sensitivities
blood sugar
activity
allergies
personal nutrition
genetic nutrition
supertasters
lifestyle & diet
microbiome
motivation
Food Safety
People
Environment
time
temperature
color
humidity
altitude
energy consumption
China, milk
& melamine
(MTHFR)
door open count
bad foods = last on list,
Insights
Hyperspectral & Multispectral imaging/spectroscopy
Personal Genetics
MTHFR
B9
folate v. folic acid
foliage v. fortified
heart health, fertility
diet, nutrition, health
Challenges
expensive camera,for now
special lighting
reflactance/sample prep
data sizes
packaged foods
meat bandwidths...
Opportunities
data play
most work so far on industry, quality, distribution
little work on consumer freshness, quality, safety
milestone deal with startup
Important Info
wavelengths
Visible
NIR
UV
food safety, presense of bacteria
fruit freshness, ripeness, bruising
beef tenderness, marbling
chicken and pork quality

If you want to do full spectrum, need 2 cameras, so 2X cost
fruits and veg, < 1000 nm
meat. 900-1700 nm
Imac (Belgium) making NIR cameras cheaper with new sensor chip
Ximea will incorporate these (supplies Fraunhofer)
2016 June, new sensor out, 40-50% drop in price for "meat cameras"

Headwall Photonics - for industrial, commercial, USDA, Oxford partner, food/biotech/security/document classification/precision ag/defense; custom pricing
Resonon - high performance, affordable price, machine vision for sorting, good video, made a request & got a specific set of specs back
Middleton Spectral Vision - industrial and research, pharma/plant sicence/mining less on food
Focal Vision and Optics - biotech
EDK - not in food, but can find debris in converor belts, production control, sorting based on invisble chemical rpoerties of goods, sort apples based on sugar content & pH

Use gold standard tech
(expensive)
to establish testing thresholds
Use consumer tech
(cheap & reliable)
in products
Important
as sensors
are upgraded
but
Industry (slow)
Consumers (fast)
Different price points adopted at different points in the channel
look to product cycles in
research: Illumina, 18 months
consumer goods: iRobot, 12 months
wellness
ecosystem opportunity
interface with a
"yum" and "yuk" list
Arivale, HLI, etc.
Faux Foods
Microbiome
environmental impact
food security
Making Leather and Meat Better
Trends: Eco Foods, Food Security 3.0
GMO 3.0
Not multinational, but family startup
Not implanted, but adjusted
Not labeled, but branded
Okanagan Specialty Fruits
Citizen Science
& Crowd-Sourced
Metagenomics
microbiome hacking
& DIY fecal transplants
Phage
Therapy
Use viruses to kill bacteria
Specifically targeted
Alternative to wide spectrum antibiotics
Developed in Russia, new Western interest
Image credit: Bacteriophages and Biotechnology
http://www.pharmainfo.net/luckypharmacist/bacteriophages
TU Munich
Beer with
lemon,
caffeine,
anti-cancer agents
Alltech
Beyond Meat
Hampton Creek
Impossible Foods
Modern Meadows
Muufri
Soylent
Teaming with
Microbes
Food Preservation
& Refrigeration?
Initiatives
To
Watch
New Foods Sector
from being in
an exponential business
Find an exponential trend,
then hitchhike
A prototype beats a plan
Product Development Process (PDP)
typical product:
18 month development cycle,
9 month market life

make new & rev old products
core team leaders involved from start
phase-gated milestones
manage technical and business risk
Nothing fades faster than last year's technology
2008
$500K
2012
$1
People
Teams
Interdisciplinary
Disruption
is never
Expected
Salim Ismail
Add a specialty
Be half of a team
Assemble a varied team
Find translators
Develop internal people
Innovation Lessons
Triple Major?
Design Your Own Major?
HACKER
"No matter who you are, most of the smartest people work for someone else" - Bill Joy
LABS
as crowdsourcing
Build a Hackerspace
Accelerator
Define a problem,
find intraprenuers
Trade access to
customers, media
BioCurious
Shenzhen's HAXLR8R
Target's Future + Food coLab
Three Word Introduction
be thinking...
Three Word Introductions
name + position
+ 3 words
First Wave Technology
Digital Biology

Food Production and Distribution
New Tech
& Business Models

Cycle 4
Cycle 5
Brain
Break

Brain
Break

Lunch
+
Bye Raymond!
Workshop: Headlines of the Future
Your team works as the editorial staff at the
New York Times
. Using these provocations as inspiration, and write the front page headlines that highlight a few of the outcomes of these new realities.
Growing animals for food is unsustainable to feed 9 billion people a day.

GMO technology is used when no other options exists.

Plant de­-extinction brings back heirloom varieties, increasing nutrients and making vegetables taste good again.

Animal de-­extinction and CRISPR gene­ editing expand our palate.

Roboticized farms make precision agriculture a possibility.

Crops are grown in the clouds.

The goal of Precision Medicine is achieved.

We are able to harvest all the data that comes off of your body.

People reconnect to resources at the local levels.

Homes only contain objects you truly love.
Workshop: Protostorming
It’s the year 2021 and you have crowdsourced funding for your own commercial accelerator Hackerlab.


Inspired by one of the headlines created in Cycle 1, and one of these newly abundant resources explored in Cycle 2, protostorm a product that works to solve a critical human need around food.

Workshop: WWxD?
It’s the year 2025 and any physical product in the home can be printed on demand.

Inspired by these new technologies in the home, design a user service journey for one of the following:

A hyper-immersive retail experience
An exquisitely elaborate dinner party
The most convenient at-home meal ever
A hyper-personalized delivery service
The process of growing and harvesting your own food
What would UberEats do?
What would Google’s Corporate Cafeteria do?
What would Alice Water’s Edible Schoolyard do?
What would Amy’s Drive-Thru do?
Workshop:
Food to Inspire Revolution

Using concepts from the day,
each team shares back their story.

It's
20 years
from now, report back on how your sector has revolutionized its corner of the world…

Tell us:
Who are you?
What is the current reality?
What needs are you solving for?
What did you create?

Reflection: Food to Inspire Community

Tracy collects reflections from participants on the following questions:

How do these ideas affect or influence your current business?

What opportunities do you see for collaboration between Innit and Pirch?

What opportunities exist for new business models moving forward?

What do you feel more confident about now than you did at the beginning of the day?

What are you excited
to share back with your team?

TU Munich
Beer with
lemon,
caffeine,
anti-cancer agents
Alltech
Beyond Meat
CellPod
Clara Foods
Hampton Creek
Impossible Foods
Modern Meadows
Nutrigene
Perfect Day/Muufri
Shojinmeat Project
Six Foods
Soylent
Initiatives
To
Watch
New Foods Sector
Sensors
Optical
Silicon
Molecular
Genetic/Bio
Quantum
Cheaper
Ubiquitous
Miniaturized
Networked
Multiphysics
Photospectrometry
Hyper- and multispectral
Molecular nanosensors
next
modes
trends
sensors
sensors
homes
kitchens
phones
appliances
families
in
sensors
farms
distribution
stores
suppliers
industry
in
Best Taste
Freshness
Safety
Tracking
uses
Biosensors
color-based
electrical-based
Ripeness Sensors
bioprinters
ethylene = fruit ripeness
biogenic amines = meat/dairy freshness
antibodies, DNA = bacterial sensing
various = contaminants
Issues:
Detect Dozens of Things
Consumables, Recharging
The
small
future
is
Vanillin
$300M
Cocoa
$2.1B
Chocolate
$131.7B
by 2019...
shifting production
global warming, disease
genetic engineering
shifting consumption
Asian markets
production innovation
health benefits
source:
Cocoa & Chocolate Market - Global Trends & Forecasts to 2019.
The Sugarbelt Bioeconomy
What areas of the world will
drive a green bioeconomy?
x
x
Land prices,
Political stability
Water access
Sunlight access
Argentina
Brazil
Uruguay
=
then
Africa
GMOs

3.0
Genetically
Modified
Organisms
better yield
better nutrition
better digestion
drought tolerance
saline soil tolerance
fungus resistance
virus resisitance
Not conglomerate, but family startup
Not implanted genes, but adjusted genes
Not labeled, but branded
Consumer acceptance
Food Security 3.0
Yield at Scale
Extraction
Displacement
Artificiality
Voluntary labeling
Market standards
IP & licensing
GMOs
Cellular
Agriculture
Digital Agriculture
Issues
2020 - the global population consumes
120 more million tons of meat
220 more million tons of milk
290 more million tons of cereals
2030 - 8 billion people
2050 - 9 billion people
2050 - 2 X milk and meat demand
more food
more feed
less water
less land
less greenhouse gases
=
color changing flowers
public-friendly, designer-y GE
IP in tools, circadian rhythm & blooms
Okanagan Specialty Fruits
E. coli
yeast
algae
Acquired by Intrexeon, Feb 2015, $41M
Glowing
Plant
Bad example
marketing by controversy
broke Kickstarter
publicity and reg around GE
animal feed
protein production
heterotrophic algae
aquaculture
breeding genomics
breweries & distilleries
privately held,
revenue doubling
GMOs
Phage
Therapy
Use viruses to kill bacteria
Specifically targeted
Alternative to wide spectrum antibiotics
Developed in Russia, new Western interest
Image credit: Bacteriophages and Biotechnology
http://www.pharmainfo.net/luckypharmacist/bacteriophages
Trends: Eco Foods
In Vivo Fermentation
limit methanogenesis
increase meat yield
biofuels - hydroxylation of methane to methanol
Implications for
ruminant digestion incubator simulator
as antibiotic
as delivery vehicle for GE Tx
Microbiome
is
old
and
new
Agriculture
=
Biotechnology
Trends: Eco Foods, Food Security 3.0
Livestock Genotyping
trait prediction
breed, pedigree, parentage
identification
outbreak traceability
David Hunt,
Co-Founder
Trends: Big Data, Ubi-Sensors, Robotics, DNA, Microbiomics
Digitizing Agriculture
Agriliarity
Agrilarity
BioBots
Moow
PIC
Stellagenomics
Sample6
Initiatives
To
Watch
Ag Tech Sector
animal feed
protein production
heterotrophic algae
aquaculture
breeding genomics
(medicine)
Microbiomes
& Metagenomics
Microbiomes
Erik Xu, Chair
$800B revenues
sensors: health & food
Ready for Prime Time?
Or next bread machine?
good preview
of things to come
Hyperlocal Farming
Vertical Farming
hyperorganic, hyperlocal
pesticide & herbicide free
Fiesta Hypermart, Houston, Texas, 1991
10,000+ sq ft hydroponic produce dept
Houston's biggest tourist attraction
Backed by NASA CELSS research group
Trends: Urbanization, Food Security 3.0
Hydroponics
Click and Grow
3D Food Printers
Kitchen Robotics
Serenti Kitchen
Edible Growth
Foodini
3D Systems ChefJet
Fast Food = Good Food
Roy Choi and Daniel Patterson
$1 $2 $4 $6
Watts
Oakland
San Francisco
Dynamic Pricing
changing prices, sometimes by the minute, given what is known about location, income and spending history of individuals, even weather
Amazon
: monitors competitors, changes prices every 10 min, with Econsultancy
Kohls
: has sales lasting hours versus days
Cintra
: Texas toll roads, every 5 min,
optimize traffic speed at 50+ mph
Travel + Apple
: more expensive options (because, wealthy)
Nebraska Furniture Mart:

monitors Amazon + Best Buy,
sets in store electronic displays every morning

+
Cow-Free
Milk & Cheese
co-founders:
Abi Ramanan
Gustav Nipe
Other Technologies
Bioreactors
Cheap & Ubiquitous Sensors
Information Flows & Deep Learning
Cellular Agriculture
positives
fewer environmental impacts
safer, purer product
more consistent supply
no harm to animals
real world examples
meat with healthier fats
milk without lactose
eggs without cholesterol
rhino horn with no extinction
negatives
the "ick" factor
Uma Valeti
CEO & Co-founder
"We want to make
safe and healthy
meat for everyone
without
hurting animals."
Mark Post
University of Maastricht
Mosa Meat
Faculty, Singularity U
environmental impact
food security
Making Leather and Meat Better
Trends: Disruption, Eco Foods, Food Security 3.0
Nutrigene
Min Fitzgerald & Van Duesterberg
CellPod
Lauri Reuter
New Harvest Conference
NYC 11&12 Oct 2017
Singularity University
Digital Biology
Future of Food
Raymond McCauley
+1-650-776-4561
with a brief appearance by
Cellular Agriculture
Full transcript