Loading presentation...

Present Remotely

Send the link below via email or IM

Copy

Present to your audience

Start remote presentation

  • Invited audience members will follow you as you navigate and present
  • People invited to a presentation do not need a Prezi account
  • This link expires 10 minutes after you close the presentation
  • A maximum of 30 users can follow your presentation
  • Learn more about this feature in our knowledge base article

Do you really want to delete this prezi?

Neither you, nor the coeditors you shared it with will be able to recover it again.

DeleteCancel

FDA Deloitte McCauley

No description
by

Raymond McCauley

on 27 August 2018

Comments (0)

Please log in to add your comment.

Report abuse

Transcript of FDA Deloitte McCauley

Democratization
of
Biotechnology
How fast can you get to
"Hello World"
with 2 guys & a laptop in a garage?
A hackerspace for biotech

First biohacker lab in the world

Committed to making biotech
accessible, affordable, and open to everyone

Located in Sunnyvale, California

501c3 all-volunteer community lab, supported by monthly memberships and classes
We teach
classes...
We mentor the
next generation
of scientists
and technologists
We support inventors
and entrepreneurs
We build
community
BioCurious/FBI
Joint Conference on
Biohacking
June 12-16, 2012
More tools in more hands
=
More Breakthroughs
We are
everywhere
...
currently tracking
23 community labs
200+ individual labs
on 6 continents
You let
kids go hands-on
with blowtorches?!?
Why, yes!
Yes we do!
5 year old Harlan
makes Calcium burn
red
.
Copenhagen
Biologigaragen.org
Let's do that for biotech!
near-zero capital costs
outsourcing ecosystem
no IP taken
new players
new uses
new markets


most innovative
education company
in the world
Top 100
#4
50+ companies out of BioCurious
$129+ Million in follow-on funding
Startups & schools copying model
Worldwide biohackerspaces
Rise of the
Biotech
Garage
Inventor
Boston
Paris
San Diego
Seattle
Oakland
Portland
Manchester UK
Biologigaragen
Biospace
Victoria, Canada
Denmark
Switzerland
Brooklyn
Sao Paolo
San Francisco
Shenzhen
Tokyo
Bio
Garage
Baltimore
Syn
Bio
Brasil
"Biology Kits"
Hands-on Tools
for Exploring
New Biology
Gene of
the Month
Club
Home Lab
Tool Stack
microscope
incubator
PCR machine
gel electrophoresis
pipettor
workspace
refrigerator
freezer
water source
waste disposal
Garage Labs, Revisited
The Platypus Project
DIY Projects
Best Biohacker tools
Next
Experiment Guides
Raymond McCauley
biochemistry
biophysics
electrical engineering
computer science
bioinformatics
nanotechnology
Exponential Biosciences
past:
Singularity
University
Raymond McCauley
Digital Biotech
Challenges for FDA
raymond@raymondmccauley.net
+1-650-776-4561
Spoiler Alert:
It's a mess, but there's a happy ending...
Journal of
Precision
Medicine
Helped develop next-gen sequencing
pharmacogenomics
personal genomics
cancer sequencing
systems biology / pathways
Co-founded first biohackerspace
Launch and develop biotech companies
What you need to know
Top-Down
Bottom-Up
Sideways-In
More Investment in Biotech
The Rise of the Biotech Billionaires
More Small Players
More Nontraditional Players
Pharma not structured
for Precision Medicine
Exponential Tech
Grassroots embrace of health tech
EIR IV
Entrepreneurs In Residence
similar to SBIR/STTR
outreach programs

Outreach & Roadshows
as "cultural exchange students"
vastly expand
win hearts and minds

genomics
personal genomics
scientific wellness
non-invasive prenatal testing (NIPT)
HBOC testing
liquid biopsies
cancer prognostics
microbiomes / metagenomics
cellspot devices
systems biology / biotech's big data
biomedical deep learning
lab robotics
advanced sensors, size and cost
biosensors
biosensing wearables
longitudinal data
implants
tissue culture
GE / CRISPR
RNA control of gene expression
CAR-T
phage engineering
DNA origami
DNA drives

Moore's Law
& Digital Biology
Top pharma execs move to small startups
Biotech milestone deal payouts doubled in 2014 ($5.6B), 2015(?)
Non-Traditional Players
not structured for regulation
+
Moore's Law for Computing
- 110 years & counting
source: Kurzweil,
The Singularity is Near
DNA Sequencing Cost
- < 20 years
Gen 1: Sanger | Gen 2: Next Gen / MPSS | Gen 3: Nanopore?
Biotechnologies undergoing Exponential Advances
More Small Players
Let's do that for biotech!
near-zero capital costs
outsourcing ecosystem
no IP taken
new players
new uses
new markets

More Non-Traditional Players
source: McCauley, Singularity University
source:
Fortune
, June 1, 2016,"Big Pharma Innovation in Small Places"
source: HBM Partners,Trends in US Drug Approvals, 2006-2015
64% of new drug approvals
in 2015 in smaller biopharma (outside largest 30).

51% of new drug approvals in 2015 from in-licensing or M&A.

Education & Entrepreneurs
2012
Janssen Labs
Diego Miralles
4 companies
in San Diego

2018
JLABS
400+ companies
9 locations
3 examples:
Scio
Scanadu
Stealth
Implants
Rock Health

Chair Digital Biology department
for Singularity University
New record:
2015 VC investment
in biotechnology
$7.4 billion
source: Price Waterhouse Cooper, Vahlos,
2016 Moneytree Report
Bill Gates
, $75.9B
#2 in world
self-made, software
Bill and Melinda Gates Foundation
gave away $28 billion
Dilip Shanghvi
, $15.1B
#44 in world, #2 in india
self-made, pharma
Sun Pharma
Caraco problems
Patrick Soon-Shiong
, $11.6B
#1 in LA
self-made, pharma
Nantworks
Cancer Moonshot 2020 initiative, with the goal of finding immunotherapy solutions for cancer
Engelhorn family (Roche), $35B
Hoffmann-Oeri family (Roche)
Dietmar Hopp, $7B
Hansjoerg Wyss, $6.1B
Randal "RJ" Kirk, $2.4B
Robert Duggan, $1.2B
Li Ka-Shing
Randy Scott
Craig Venter
Eric Xu
Peter Thiel
, $2.7B
Facebook & Palantir investor
Breakout Labs, Founders Fund
Libertarian; Gawker feud
The Breakthrough Prize

$3M, 6 for Life Sciences
founded in 2013 by
Sergey Brin and Anne Wojcicki
Mark Zuckerberg and Priscilla Chan
Yuri and Julia Milner
Jack Ma and Cathy Zhang
More Investment in Biotech
The Rise of the
Biotech Billionaires
Full transcript