Transcript: good ideas Sitting together and making agreements The first problems gain more information from the start to specify the assignment Good start but ended up a bit lost on what to do Questions? TMQIO Project plan Feedback Team roles better PDCA company Misinterpretation of information given by lecturer Team members Patricia Peukert Lisanne van't Blik Maike Slater Bjorn Huberts almost all communication through facebook wrong expectations on what to deliver Planning Lisanne: monitor evaluator > completer finisher Bjorn: team worker > implementer Maike: team worker Patricia: specialist > completer finisher new agreements had to be made TEAMWORK!!! Next time we should make sure we have the right information on time to hand in a sufficient report Good start Thank you for your attention Starting up Our first problems Project plan feedback Sitting together and making agreements Planning Risks End result + conclusion What and how to do it better next time What and how to do it better next time Starting up since we started very fast motivation disappeared communication motivation not sticking to agreements and deadlines a few problems occured 15/10 evaluation 26/10 product presentation for client End 2015 App development enthusiastic Risks The iFood restaurant at Stenden University formulating and signing working agreements effective communication sticking to schedule Table of Contents End result + conclusion Project Management Presentation better communication sticking to deadlines share the same goals
Transcript: Positive Team presentation: -DSTT Sports project -The opportunity to expand our operations across the nation. -Increase profits. Prepared by: -Shafiq Kuttab -Taylor Hughes -Tristan Jones-McCrea -Dakorion Desamme Opportunities -The supplier is willing to add another location to the contract. -Operating expenses will be similar to the other stores' operating expenses. -Bank rate remains constant. -Design company will finish decorating the store accurately and on time. -Advertisements will be correct. Overview -Under-budgeting. -Competition. -Business exposure Assumptions Probability-Impact Matrix Continually monitor the schedule and the budget comparing the projected cost and projected work completed with the actual cost and actual work completed. Other metrics include continual feedback from managers and members of the project. Quality Metrics Project Execution Why are we doing this project? Vs. WBS -Under-spending -High market share -Exceed projected foot- traffic. -Close proximity to supplier. -Close to university, which would essentially provide foot traffic. -Lack of sports stores in area. -Cost-effective store. -Familiar with operations Schedule and Budget Risks Negative
Transcript: Methodology New era Successors of Frederick Winslow Taylor Frederick Taylor in his work, “The Principle of Scientific Management”, give us a description of how the implementation of scientific methods to the management of workers, can help us improve the productivity. The 2 main scientific methods, Taylor implement to study the problems of administration are the observation and measurement of the factors. Objectives Frederick Winslow Taylor provided the basis for further conceptual development. Taylor principles lead to the Scientific Management of Business, creating a school of thought that later would be called as Taylorism . Its development was based on the observation of differences in worker productivity , which found due to several causes , such as differences in talent , intelligence, or motivations. He was one of the first to notice the existence of these differences , analyze and define aimed at improving profit improving efficiency and standardizing processes methods. Company basing on the doctrines of Taylor, began monitoring their workers in this study were conducted, three aspects were considered: • Time to perform a task. • Number of tasks the worker do. • How motivated was the worker. Conclusion Case This work structure is separated into different phases (evaluation of technical feasibility and economic-financial , planning, implementation , closing and control) to optimize the use of resources while minimizing the risks REVIEW OF RELATED LITERATURE CONCLUSION A company dedicated to the commercialization of sacks of flour in Venezuela, known under the name of “Harina P.A.N”, wanted to optimize performance. The business problem was that the effectiveness of its workers was declining, compared to past months. Frederick Winslow Taylor Ancient era Jusification of the investigation The beginning of project management Project Management will give impetus to their theories and design tools to transform the way we understand the process. The purpose of management is to coordinate all available resources to achieve certain objectives, this implies the interaction between knowledge, technology, environment, structures, processes, services and products. In this sense, management solutions and project management (methodologies, techniques, technologies, models, tools) must support the project management process. This process in turn should be successful, based on reasonable principles. The first, designed a tool for monitoring and recording the progress of the work at different stages of project planning : it the diagram Gantt Wal-Mart's Global Expansion in Mexico. COLLECTING DATA TECHNIQUES THEORY ON THE RESEARCHING It is clear that not all workers in the company have the physical capacity to load 25 tons per day, you could say that only one eighth of workers could. This case suggests that workers should be able to do engage in this particular activity, the loading sacks of flour, the other should be placed in jobs commensurate with their abilities. Learn how project management works The two American moon landing : Neil Armstrong and Edwin Aldrin. The birth of the ARPANET. the French mining engineer Henry Fayol , developed the first modern theory of management , defining six primary functions of management which are still valid : 1.Forecasting 2.Planning 3.Organizing 4.Commanding 5.Coordinating 6.Monitoring. The mythical construction of Noah's ark and the construction of the Egyptian pyramids. Identify each one of the steps of the project management cycle and how does each one works for the achievement of the project. How project management can be used for a correct management of the staff getting a better performance in the work that they do. The project management works in a way that, we can program in an efficient way different tasks that are carried out during different phases on the project. Identify some barriers that we can find in the implementation of a project. Show how a project management can be success for the achievement of our objectives. RECOMMENDATIONS
Transcript: ASH-123 Cancer Innovation in Canada Novel Oncology Therapeutics INTRODUCTION Project: A Phase I Study for the Treatment of Advanced and Recurrent Gynecological Cancers using novel agent ASH-123 Description: Initiation of a phase 1 study using ASH-123 will address current gynecological treatment needs, and progress the knowledge of how the ASH-123 molecule responds in humans with regards to toxicity, and tolerability. INTRO Average cost of bringing a new drug to market is $1.3 billion, a price that would buy 371 Super Bowl ads, 16 million official NFL footballs, two pro football stadiums, pay of almost all NFL football players, and every seat in every NFL stadium for six weeks in a row. -Eli Lily, 2012 The American Cancer Society estimated that about 6% of the 1.6 million new cancer cases diagnosed in the US in 2013 were women with a gynecologic cancer (Andrews et al., 2013). Ovarian cancer is the most fatal gynecological malignancy, with an overall 5-year survival rate of 44%. (Siegel et al., 2011) Tumor suppressor protein p53 prevents cancer development by eliminating and inhibiting the proliferation of abnormal cells (Levine, 2009). TP53 is the most commonly mutated gene in human cancer with a frequency of mutations ranging from 38% to 96% (Kandoth et al., 2013; Freed-Pastor & Prives, 2012). In fact, p53 is mutated at a high frequency in the majority of aggressive tumors including 96% of ovarian cancers, 85% of basal breast cancers and over 50% of lung cancers (The Cancer Genome Atlas Research Network, 2011; 2012a; 2012b). Issue Issue Currently Upon diagnosis, women typically undergo cytoreductive surgery followed by platinum- and taxane-based chemotherapy. This treatment leads to a complete remission in over 70% of women, however, the majority of these patients will relapse and eventually die from the disease. There are numerous therapeutic options to treat relapsed ovarian cancer, including combination chemotherapeutic regimens and biologic agents (Raja et al., 2012), although none of them have led to a cure, and the best outcome of current treatment in the recurrent setting remains palliation. Background and Current Situation Background and Current Situation ASH-123’s primary mechanism of action involves the restoration of p53 function in to wide range of common p53 mutations. The p53-independent mechanism of action can be attributed to its ability to modulate the PI3K/AKT/mTOR signaling pathway. ASH-123 ASH-123 Utilization of ASH-123 in a human gynecological cancer population for the purpose of gaining further knowledge about the toxicity profile of the drug, and the maximally tolerated dosing level to create a recommendation of the phase 2 dose. Recommendation Recommendation Anticipated Outcomes 1 Toxicity and tolerability levels will fall within expected range Maximally tolerated dose will be identifed to allow further testing in a Phase 2 setting The maximally tolerated dose will be at a maximal beneficial level Early signs of efficacy will be seen through response criteria 2 3 4 Anticipated Outcomes Phase 1 Study ASH-123 A novel oncology treatment Project Objectives Project Objectives Primary Objectives •To evaluate the safety and tolerability of ASH-123 in patients with advanced and recurrent gynecologic malignancies. •To determine the maximum tolerated dose (MTD) and recommended Phase 2 dose (RP2D) of ASH-123 for the treatment of patients with advanced and recurrent gynecologic malignancies. Secondary Objectives •To evaluate the pharmacokinetics of ASH-123 at all dose levels in patients with advanced and recurrent gynecologic malignancies. •To estimate the clinical activity of ASH-123 at the RP2D in patients with advanced and recurrent gynecologic. malignancies by response rate (RECIST criteria) and the proportion of patients surviving progression-free at 6 months •To estimate the response duration for ASH-123 at all dose levels in patients with advanced and recurrent gynecologic malignancies. Exploratory Objectives •To determine if baseline molecular aberrations, including p53 mutation, correlate with activity of ASH-123 in advanced and recurrent gynecologic malignancies. •To evaluate pharmacodynamic markers of ASH-123 activity at the RP2D in patients with advanced and recurrent gynecologic malignancies. TEAM Chris Lynam Director of Clinical Operations Ashley ten Haaf Clinical Trials Manager TEAM Organizational Impact Creation of new roles Statistics Project Managment Medical monitoring Site Coordination Data Management Scientific Writting Biological Sample Analysis Data Monitoring Safety Management Supplies Managment Administration Partnership with new Vendors Clincal Research Organization Central Laboratories Study Sites Suppliers/Distributers Couriers Electronic Data Capture Software Trial Managment Software Michelle Jones Study Monitor Dr. Johnson Korie Medical Monitor Craig Johnson Study Coordinator Sara Campbell Data Manager Dr. Shannon Westin Principal Investigator This is a single arm,
Transcript: Building process - It can be applied onto gas chainsaws - Automatic threshold adjustment - Completely new designed chainsaw to accommodate SawStop with no retrofits It will help eliminate injuries to the operator where the kickback brake cannot Propose Ideas to manufacturers Advertisement Risks Delegate certain sections of the project to each of our four group members. Problem Statement To create a saw stop technique implemented onto a chainsaw Same technology in the "Saw Stop" table saw adopted by the chainsaw Marketability - The product breaks itself upon initial test. - Cannot get the product to work Voltage is monitored by a micro controller More than 36% were injuries to the legs and knees. - A safety device that is built into a chainsaw The Problem ChainStop Estimated budget for the project: $500 It uses a small electrical charge that is induced into the bar of the chainsaw 28,500 chain saw injuries in 1999 in the United States and that number continues to go up. Start date: May 2016 Expected completion date: December 2016. Outcome Exercise our resources to collaborate and work effectively to complete it on time. How does it work By: Jan Cortez and Murray Dale The Solution Scheduling What we will accomplish How can this project be expanded
Transcript: Who are Project Managers? References PMBOK® Guide – Sixth Edition (2017). What is Project Management? Retrieved from: https://www.pmi.org/about/learn-about-pmi/what-is-project-management Why learn Project Management? Project managers are change agents Comfortable with change and complexity in dynamic environments. People skills, broad and flexible techniques How does it work? Harvard Business Review Staff. (November 03, 2016). The Four Phases of Project Management. Retrieved from: https://hbr.org/2016/11/the-four-phases-of-project-management Quality = Time + Cost The value of project management is proved by the rapid, worldwide growth of : as a recognized and strategic organizational competence as a subject for training and education as a career path Project management processes: 1. Initiating 2. Planning 3. Executing 4. Monitoring and Controlling 5. Closing Project Management Project Management and its future The application of knowledge, skills, tools, and techniques to project activities to meet the project requirements. What is Project Management? Project Management Impact: Professionalism Volunteerism Community Engagement Project: temporary, unique Accomplish a specific goal Time, budget Project Management Lois Zheng LDRS 420 Presentation
Transcript: Value Management By: Josh Ruehlow Prior to design stages For dynamic and unstructured problems Usage in Project During all different stages After project is over budget Best on small scale For static, well defined problems Value Management for Building Projects Increase value, and reduces price Chooses least expensive design No consideration to quality, reliability, performance, or delivery Usage in Project Creates a framework for decision making Early attention to problems Early involvement from stakeholders Increases communication and trust Conclusion Value Engineering Soft systems thinking Creates common understanding of problems and objectives Fosters collective thinking Impact on Project Impact on Project Introduction Hard systems thinking Application of standard problem solving Assumes designs have same function Minimizes costs
Transcript: Strategic Project Management - Project life-cycle (deadline management) - External (customer) feedback Business Management & Leadership Team Dynamics Employees Agile - SCRUM methodology adopted Cognitive Coaching Feedback Me martin Stress Friends - Final Product and Features - Internal (project) feedback Formal or Informal Situational Leadership Project definition & Requirements - RIsk management (internal/external) Human Understanding - Product Delivery Evaluation Families Risk Management Full Engagement Technology The Brain - Resource management
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