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Nanomedicine Targets Cancer

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Chris Ciccarelli

on 1 December 2010

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Transcript of Nanomedicine Targets Cancer

Targets Cancer Creating a System Requires an ample amount of data, living organisms, something that can be measured, quantified and programmed into the model.

The computer system requires an integration of mRNAs and protein levels to properly distinguish the organism’s transition from healthy to diseased.

Large scale measurements of mRNA and protein concentrations have revealed that traditional approaches to cancer are inadequate since cancers are identified as separate diseases. Detecting Disease Analyses of mRNAs and proteins from tumour tissues can be informative to distinguish between healthy and diseased cells.

The ability to detect an imbalance in particular proteins or mRNAs could therefore serve to signal the presence of disease and pinpoint its location and its nature. Measuring Molecules Miniaturization of devices can offer better precision and radically faster measurements than can be achieved with current technologies.

The four-centimetre-wide chip that tests protein levels in a droplet of blood, applying a highly miniaturized alternative to conventional protein detection strategies

After the plasma has been sampled, fluorescent tags washed across the barcode collection attach only to protein bound antibodies. Directly Targeted Nanoparticles which are enclosed by a capsule, target antibodies and other molecules which when bound to proteins can be added to a particle’s surface.

Problems arise with the size of the particle.

Nanoparticles are accustomed to accumulate in tumour IT-101 IT-101 is a 30-nm particle gathered from polymers joined to the small-molecule drug camptothecin, which is closely related to two chemotherapy drugs.

As the drug is released, the rest of the nanoparticle components disassemble and the small individual polymer molecules harmlessly exit the body through the kidneys. Designed Devices Quantum Dots Nanoshells Nanoparticles Nanowires A nanowire can have the properties of an insulator, a semiconductor or a conductor.

When a protein meets its matching antibody, it binds to the probe and changes the conductive properties of the wire, allowing the event to be detected electronically.
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