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tb

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by

ahmad aladl

on 16 December 2013

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Transcript of tb

T B
Reservoir
Humans: primarily the lungs
mode of infection
ingestion
airborne: inhale droplets
type of TB infection
Target Cells/Tissues/Organs within Host
Colonize and multiply in the lungs
Live/replicate/infect macrophages: triggers inflammation and damage
Works Cited
http://textbookofbacteriology.net/tuberculosis_3.html
http://www.cdc.gov/tb/publications/factsheets/drtb/mdrtb.htm
http://radiographics.rsna.org/content/26/5/1449/F17.expansion.html
Symptoms
A bad cough lasting longer
than 3 weeks
Pain in the chest
Coughing up blood
Weakness or fatigue
Weight loss
No Appetite
Chills
Fever
Sweating at night
Diagnosis
1. Medical History

2. Physical Examination

3. Test for TB infection

4. Chest Radio graph

5. Diagnostic Microbiology

6. Drug Resistance
definition:chronic infective granuloma affecting nearly all systems mainly lung
Tuberculosis bacili
Second Line Defense
pathogenesis
cause
direct contact

1ry T.B
2ry T.B
young ages
non immunized persons
middle age
patient taking B.C.G vaccine
methods of infection
methods of infection
1-inhalation
2-ingestion
3-direct contact
1-endogenous due to reactivation
2-exogenous due to reinfection
site of 1ry complex
site of 1ry complex
lung,intestine,skin,tonsils nose
any site mainly lung ,intestine
complication
complication
spread mainly lymphatic, blood
spread mainly local,natural passage
proliferative raction
primary complex formed of
1)tubercle with caseation
2)T.B lymphadenitis
3)T.B lymphagnitis
*proliferative raction in solid organ
*exudative reaction in serous
**N/E of tubercle
tubercle is 1-3 mm with central
yellow
caseation
grey white
periphery
**M/E of tubercle
cuntral caseas material(easinophlic) epithliod cells,
macrophages,giant cells,lymphoctes ,peripheral fibroblastic reaction
pulmonary T.B
1ry pulmonary complex formed of
ghon's focus
T.Blymphagnitis
T.B lymphadenitis
fate
1)good:healing
2)bad:spread
miliary T.B
definition:
sever form of T.B due to blood spread of large dose of T.B bacili in apatient with very low immunity
T.B enteritis
1ry intestinal complex
1)intestinal parenchymatous lesion
2)T.B lymphaginitis
3)T.B lymphadenitis
fate:
good:healing
bad:spread
2ry itestinal complex
ulcerative type
hyperplastic type
complication
1-hemorrhage
2-intestinal obstruction
3-fecal fistula
4-spread
5-amyliodosis
T.B of vertebrae (pott's disease)
2)cold abscess
complication
1)deformity
site
posterior mediastinal
psoas abscess in the inguinal region
3)secondry amyloidosis
4)paraplegia
renal tuberculosis
source of infection:
-blood spread
-ascending from the U.B
result in:
1)T.B pyelonephritis
2)miliary T.B
3)tuberculoma
T.B pyelonephritis(surgical kidney)
affection may be unilateral or bilateral
grossly
kidney is enlarged,bosselated.C/s show white caseous material filling the pelvicalyceal system
by
1-Ahmed El-Adl
2-Ahmed Zaki
3-Ahmed Salah Ali
4-Ahmed Abd El-Razik
5-Ahmed El-Ashry
T.B of male genitale tract
less common
affect mostly epidydims prostate ,seminal vesicle
if it ulcerate it open as aposterior sinus
T.B of femalegenital tract
T.B Salpingitis
cause infertility

2ry pulmonary T.B
assman-simans focus
fate

1)good
2)Bad
-cavitary fibrocaseas T.B
-spread
-fibrosis
-tissue distruction
Full transcript