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Mitosis

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Ariel Ash-Shakoor

on 26 January 2015

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Transcript of Mitosis

Mitosis
But First, Let's recall information from the previous class lesson
Where is the genetic information of a cell stored?
1) Mitochondria
2) Proteins
3) Nucleus
4) Golgi Apparatus

What cell cytoskeleton protein is responsible for cell movement?
1) Actin
2) Myosin
3) Microtubules
4) Intermediate Filaments
5) Actin and Myosin
6) Actin and Microtubules
7) Actin and Intermediate Filaments
8) Actin, Microtubules, and Intermediate Filaments

1) Estimate the amount of cells that can be made by your body?

2) What kind of cells was made during this time period? What kind of cells remained dormant?
Please discuss..

1) How can 1 cell become 2 cells?

2) What should a new cell retain from the previous cell into a new cell? Why?

Next Class...
Prophase
Cytokinesis
Review and Assessment
Spindle Checkpoint!
Chromosomes do not separate until:
1. All attachment errors are fixed
2. All chromosomes have bipolar attachment

Why is it important for the cells to have check points?
Cell
1. Intermediate filaments disassmble
2. Golgi and ER fragment
3. Endocytosis and Exocytosis cease
Nucleus
1. Chromosomes Condense
2. Microtubulues on centrosome change into
radial arrays of 2 short microtubules

Asters are 2 radial arrays of short microtubules
Chromosomes are located at the middle of the cell termed the metaphase plate
Nuclear envelope reassmbles
Cleavage furrow constricts
Central spindle assembles
Spindle poles continue to separate
Anaphase A: Sister Chromatids separate
Anaphase B: Spindle Poles move apart

Cell: Golgi apparatus begins to reassemble
Prometaphase
Metaphase
Telophase
Anaphase
Predict Ways to Cure Cancer
Objectives
Explain the importance of mitosis
Form hypothesis about natural phenomena
Compare and contrast hypotheses with results

Identify phases of mitosis
Know how to draw the phases
Recognize the phases given a picture
Explain the main process of each phase

Answers:
1) Nucleus
2) Actin and Microtubules
Onion Root Cells
Cell Biology 101
Lesson 5: Mitosis
Before I begin with the lecture....
For a large and actual class,
Flipped classroom approach
Detailed clicker quiz on reading from the previous night
Broad, main points discussed in class with options for detailed questions
Prezi is available online after class
Students are expected to read before class, review information in an introductory prezi, and complete weekly homework assignments
Quizzes and homework focus on technical jargon and detail
Class activity format will accomodate larger class
Late Prometaphase
What happens when the cell cycle goes wrong?
Daughter cells separate
Main Steps
1. Nuclear envelope dissassembles and disperses into cytoplasm
2. Chromosomes attach to microtubules at specific locations, kinetochores
3. Chromosomes begin to align in the middle of the cell
Early Prometaphase
Nuclear envelope disassembles
Microtubules grow and shrink in aster
kinetochore captures microtubule
Chromosome slides along microtubule
Microtubule attached to opposite spindle
Chromosome moves to middle of spindle
Early cytokinesis
Late Cytokinesis
New Membrane inserted
Acto-myosin contraction ring forms at intersection of cells
Midbody begins to form
Chromatin decondenses
Nuclear substructures reform
Interphase microtubule array reassembles
Centrosome
Microtubules
Sister Chromatids
Cell Biology 101
Kinetochore
Centrosome
Metaphase plate
Daughter Cells
References for pictures and videos
Phases of cell mitosis micro.magnet.fsu.edu
Lung cancer pharmaceutical-networking.com
Cell cycle abenagh.pbworks.com
onion root sci.mpls.k12.mn.us
wheel of fortune tvrage.com
cell biologyjunction.com

youtube videos
csi opening theme by jpn27
Twilight Mitosis Video - Edited for Educational Purposes by cmbbiology
cell division on contrast microscope by lonvon
Questions?
Chromosome
Chromatid - A single chromosomal DNA molecule and its proteins
Sister Chromatid- Products of DNA replication, 2 identical DNA molecules packaged by chromatin protein
Chromatin- DNA and proteins that package it in the nucleus
Chromosome- DNA with protein that behaves as independent unit during mitosis and meiosis
Nucleus
Nuclear envelope- Double lipid bilayer that encloses the nucleus; outer membrane continuous with ER
Nucleolus-Nuclear subdomain for ribosome biogenesis
Nucleus- Membrane bound compartment in eukaryotes containing genomic DNA and machinery for RNA synthesis and processing
Microtubules
Microtubules- Stiff cylindrical polymers of alpha and beta tubulin that support a variety of cell structures and serve as tracks for motor proteins, kinesis and dynein
Centrosome- Pair of centrioles and surrounding matrix containing proteins including gamma tubulin that nucleate microtubules and serve as microtubule organizing center
Vocabulary
Full transcript